Biomolecular concepts

Biomol Concepts · ISSN (e) 1868-503X · 3 papers in corpus
review 2023
A commentary on the inhibition of human TPC2 channel by the natural flavonoid naringenin: Methods, experiments, and ideas
doi:10.1515/bmc-2022-0036 ·PMID:37677148

Human endo-lysosomes possess a class of proteins called TPC channels on their membrane, which are essential for proper cell functioning. This protein family can be functionally studied by expressing them in plant vacuoles. Inhibition of hTP…

review 2019
Endometriosis Pathoetiology and Pathophysiology: Roles of Vitamin A, Estrogen, Immunity, Adipocytes, Gut Microbiome and Melatonergic Pathway on Mitochondria Regulation
doi:10.1515/bmc-2019-0017 ·PMID:31339848

Endometriosis is a common, often painful, condition that has significant implications for a woman's fertility. Classically, endometriosis has been conceptualized as a local estrogen-mediated uterine condition driven by retrograde menstruati…

2014
Epigenetic regulations through DNA methylation and hydroxymethylation: clues for early pregnancy in decidualization.
doi:10.1515/bmc-2013-0036 ·PMID:25372745

DNA methylation at cytosines is an important epigenetic modification that participates in gene expression regulation without changing the original DNA sequence. With the rapid progress of high-throughput sequencing techniques, whole-genome …