Reproductive BioMedicine Online

Reprod Biomed Online · ISSN (print) 1472-6483 · ISSN (e) 1472-6491 · 447 papers in corpus
other 2020
doi:10.1016/j.rbmo.2020.07.012 ·PMID:32819840

Oocyte vitrification is an attractive and efficient option in the long-term management of endometriosis patients. Which women would benefit from banked oocytes when pregnancy is attempted, and whether oocyte vitrification should be carried …

other 2020
doi:10.1016/j.rbmo.2020.03.020 ·PMID:32709523

RESEARCH QUESTION: Do endometriotic lesions undergo endothelial-mesenchymal transition (EndoMT)? DESIGN: Lesion samples from 30 patients with ovarian endometriomas and deep endometriosis, and control endometrial tissue samples from 30 wome…

observational 2020
doi:10.1016/j.rbmo.2020.07.022 ·PMID:32873492

RESEARCH QUESTION: The major causes of IVF failure in women with endometriosis have been attributed to decreased ovarian reserve, low embryo quality and impaired receptivity of the endometrium. Dienogest (DNG) has anti-inflammatory and anti…

other 2020
doi:10.1016/j.rbmo.2020.11.012 ·PMID:33349531

RESEARCH QUESTION: What is the evolution of adenomyosis on magnetic resonance imaging (MRI) after a 3-month treatment course of daily 5 mg doses of ulipristal acetate (UPA) for symptomatic fibroids? DESIGN: A monocentric prospective pilot …

other 2020
doi:10.1016/j.rbmo.2020.06.005 ·PMID:32620464

The purpose of this Commentary is to assess whether the designation by New York State Department of Health of 'sexual and reproductive health services as essential' is consonant with the seemingly divergent objectives of providing patient-c…

observational 2020
doi:10.1016/j.rbmo.2020.08.009 ·PMID:33077356

RESEARCH QUESTION: What are the perinatal outcomes and especially the risk of small for gestational age (SGA) babies born after frozen versus fresh embryo transfer in mothers affected by endometriosis undergoing treatment with assisted repr…

other 2020
doi:10.1016/j.rbmo.2020.04.006 ·PMID:32651107

RESEARCH QUESTION: Does sodium tanshinone IIA sulfonate (STS) induce cellular senescence in endometriotic lesions and thus restrict lesional development and fibrogenesis in a recently established mouse model of deep endometriosis? DESIGN: …

observational 2020
doi:10.1016/j.rbmo.2020.07.027 ·PMID:32972873

RESEARCH QUESTION: Does adenomyosis affect IVF independent of decreased ovarian reserve, and what are the characteristics and IVF outcome of the ultra-long gonadotrophin-releasing hormone (GnRH) agonist protocol in adenomyosis? DESIGN: Obs…

meta-analysis 2020
doi:10.1016/j.rbmo.2020.04.014 ·PMID:32600946

The success rate of medical and surgical treatment for endometriosis is limited. Empowering patients suffering from endometriosis by giving them opportunities to positively influence their symptoms could result in increased quality of life.…

observational 2020
doi:10.1016/j.rbmo.2020.09.002 ·PMID:33046374

RESEARCH QUESTION: Is there a follicular fluid-specific metabolic profile in deep infiltrating endometriosis (DIE) depending on the presence of an associated ovarian endometrioma (OMA) that could lead to the identification of biomarkers for…

review 2020
doi:10.1016/j.rbmo.2020.11.013 ·PMID:33384269

The freeze-all strategy is gaining popularity worldwide as an alternative to the conventional fresh embryo transfer. It consists of cryopreservation of the entire embryo cohort and the embryo transfer in a subsequent cycle that takes place …

observational 2020
doi:10.1016/j.rbmo.2020.03.003 ·PMID:32475752

RESEARCH QUESTION: Available evidence shows that the presence of ovarian endometriomas does not interfere with the ovarian response to ovarian stimulation. However, the mean size of the endometriomas in these studies is generally small, and…

observational 2020
doi:10.1016/j.rbmo.2020.02.011 ·PMID:32376315

RESEARCH QUESTION: Adenomyosis has been reported in a high proportion (24.4%) of infertile women, but this may be over-representative. What is the exact prevalence of adenomyosis in an infertility clinic population? DESIGN: In this cross-s…

lab-animal 2020
doi:10.1016/j.rbmo.2020.09.012 ·PMID:33109440

RESEARCH QUESTION: Endoplasmic reticulum stress (ERS) is caused by the accumulation of the misfolded or unfolded proteins in the endoplasmic reticulum and induces the unfolded protein response (UPR). Peritoneal fluid is important in the pat…

other 2019
doi:10.1016/j.rbmo.2019.11.007 ·PMID:32362572

RESEARCH QUESTION: How closely related are adenomyotic and endometrial glands? DESIGN: In this study, the mRNA and protein database www.proteinatlas.org was searched for proteins expressed predominantly in the endometrial glands. Specifici…

other 2019
doi:10.1016/j.rbmo.2019.04.013 ·PMID:31204258

A recent article supports our longstanding view that all intramural fibroids can cause disturbance of uterine function. This may be reflected in the symptom of menorrhagia or fertility-related issues, as well as pregnancy losses at all gest…

observational 2019
doi:10.1016/j.rbmo.2019.06.006 ·PMID:31378689

RESEARCH QUESTION: The study aimed to assess the associations between pre-operative symptoms in patients with deep infiltrating endometriosis (DIE) and intraoperatively determined extent of disease as described by the revised ENZIAN score. …

observational 2019
doi:10.1016/j.rbmo.2019.01.011 ·PMID:30981619

RESEARCH QUESTION: Is there any relationship between numbers of FOXP3+ regulatory T-cells (Treg) and occurrence of peritoneal lesions in women with ovarian endometrioma and dermoid cysts? DESIGN: Retrospective and prospective case-controll…

meta-analysis 2019
doi:10.1016/j.rbmo.2019.05.021 ·PMID:31735549

Endometriosis and atherosclerotic cardiovascular disease (ASCVD) share similar pathogenic mechanisms. Hence, this systematic review evaluates the association between endometriosis and lifetime ASCVD risk including co-prevalence with dyslipi…

other 2019
doi:10.1016/j.rbmo.2019.03.210 ·PMID:31160242

RESEARCH QUESTION: Is there a biological difference between intrinsic and extrinsic adenomyosis with coexisting deep infiltrating endometriosis (DIE)? DESIGN: In this prospective controlled study, biopsy specimens were collected after surg…

observational 2019
doi:10.1016/j.rbmo.2019.05.014 ·PMID:31427176

RESEARCH QUESTION: Immunological disorders have been reported to promote the progression of endometriosis. Several recent studies have shown that myeloid-derived suppressor cells (MDSC) drive the progression of endometriosis. The aim of thi…

lab-animal 2019
doi:10.1016/j.rbmo.2019.05.019 ·PMID:31377021

RESEARCH QUESTION: Endometriosis is a common gynaecological disease defined by the presence of endometrium-like tissue outside the uterus. This complex disease, often accompanied by severe pain and infertility, causes a significant medical …

observational 2019
doi:10.1016/j.rbmo.2018.11.034 ·PMID:30928300

RESEARCH QUESTION: The prevalence of infertility in couples actively trying to conceive is 25%. What is the consultation-seeking behaviour, diagnosis and related treatment in infertile couples across China? DESIGN: Large cross-sectional po…

meta-analysis 2019
doi:10.1016/j.rbmo.2019.11.003 ·PMID:31926826

RESEARCH QUESTION: Women with endometriosis are considered to be at higher risk of several chronic diseases, such as autoimmune disorders, gynaecological cancers, asthma/atopic diseases and cardiovascular and inflammatory bowel diseases. Co…

lab-animal 2019
doi:10.1016/j.rbmo.2019.10.001 ·PMID:31787549

RESEARCH QUESTION: Endometriosis is characterized by the occurrence of endometrial-like tissue outside the uterus. Collagen triple helix repeat containing-1 (CTHRC1) is known as a tumour-promoting factor in several neoplasms. This study aim…