Drug Development and Industrial Pharmacy

· ISSN (print) 0363-9045 · ISSN (e) 1520-5762 · 1 paper in corpus

article 2006

Supersaturation Produces High Bioavailability of Amorphous Danazol Particles Formed by Evaporative Precipitation into Aqueous Solution and Spray Freezing into Liquid Technologies

doi:10.1080/03639040500529176 ·PMID:16720411

The bioavailability of high surface area danazol formulations was evaluated in a mouse model to determine what effect high supersaturation, as measured in vitro, has on the absorption of a poorly water soluble drug. Danazol, a biopharmaceut…