Medicine

This study investigates the mechanism of Ge Xia-Zhu Yu decoction (GXZYT) in the treatment of endometriosis (EMS). The active components and targets of GXZYT were screened using TCMSP database and HERB database. The EMS-related genes were re…

To analyze the significance of endometrial thickness (EMT), endometrial volume and uterine peristalsis (UP) for forecasting the pregnancy outcome of patients with adenomyosis (ADM) undergoing frozen embryo transfer (FET). Women diagnosed wi…

Small bowel obstruction in virgin abdomen (SBO-VA) is rarely encountered and there is no standard treatment strategy. Even though nonoperative management is advocated in recent studies, studies evaluating the outcomes and results of laparos…

RATIONALE: Ovarian clear cell carcinoma (OCCC) during pregnancy is exceedingly rare, particularly when accompanied by squamous differentiation, with only a limited number of cases reported in the English literature to date. PATIENT CONCERN…

Epidemiological studies have reported gender disparities in asthma, suggesting female reproductive traits may play a role, though causality remains unclear. We used summary data from genome-wide association studies on 12 female reproductive…

Endometriosis is a chronic inflammatory estrogen-dependent inflammatory disorder. Theobromine has been implicated in diverse health benefits, including anti-inflammatory and vasodilatory properties. However, the precise association between …

Sequelae of pelvic inflammatory disease (SPID), such as chronic pelvic pain and infertility, are major long-term complications that significantly harm women's health. N6-methyladenosine (m6A), the most common internal mRNA modification in e…

RATIONALE: Horseshoe appendix is 1 of the rarest types of duplex appendix characterized by 1 appendix having 2 openings at the cecum. Clinically, it is extremely rare and is detected incidentally at surgery. Therefore, accurate and timely d…

Endometriosis (EM) significantly impacts the quality of life, and its diagnosis currently relies on surgery, which carries risks and may miss early lesions. Noninvasive biomarkers are urgently needed for early diagnosis and personalized tre…

Atherosclerosis (AS) is a systemic disease closely related to inflammatory cell infiltration and immune cell activation, often leading to myocardial infarction and stroke and is the leading cause of death worldwide. AS is asymptomatic in it…

Adenomyosis (AM) is recognized as a complex gynecological and endocrine disorder that contributes to infertility and elevates the risk of pregnancy complications; however, its underlying genetic basis remains unidentified. This study aimed …

This study aimed to develop a multivariable predictive model for early identification of infection risk in patients with acute pancreatitis (AP) complicated by systemic inflammatory response syndrome (SIRS) and to evaluate the clinical impa…

BACKGROUND: To evaluate the effect of laparoscopic procedures integrated with traditional Chinese medicine (TCM), specifically aimed at enhancing blood flow and alleviating blood stasis, on oxidative stress levels in individuals with endome…

BACKGROUND: Homeobox genes (HOX) are the basic molecules that regulate endometrial receptivity, decidualization, and progesterone response. This study was designed to investigate the effects of the classical hysterosalpingography (HSG) proc…

This study attempted to evaluate the incidence of incidentalomas based on computed tomography (CT) in colorectal cancer (CRC) patients. CRC patients who obtained plan or enhanced CT for the whole abdominal and pelvis were included at the Fi…

This study aims to identify angiogenesis-associated genes (AAGs) in endometriosis (EM) by integrating bioinformatics analysis with machine learning, and to investigate their underlying mechanisms. Differentially expressed genes (DEGs) were …

Endometriosis is referred to as a "benign cancer," severely impacting women's reproductive health. However, the pathogenesis of endometriosis remains unclear. This study aims to investigate the potential roles of lipid metabolism-related ge…

Aspartame is a nonnutritive sweetener derived from phenylalanine and is widely used in food and beverages globally. In recent years, its safety, particularly the potential carcinogenic risks, has garnered significant attention; however, the…

This study aimed to describe the association between the total antioxidant capacity, phytochemical index (PI), and dietary inflammatory index (DII) of the diet and ongoing pregnancy rate in infertile couples undergoing in vitro fertilizatio…

Endometrial cancer (EC) is a major reproductive system tumor and a common cancer in women. Polycystic ovary syndrome (PCOS) is one of the most prevalent female reproductive endocrine disorders. The incidence of EC is significantly higher in…

RATIONALE: Intramural pregnancy is a rare form of ectopic pregnancy in which the gestational sac is embedded entirely within the myometrium, with no connection to the uterine cavity. Early diagnosis and timely management are challenging. P…

RATIONALE: Adenomyoma of the broad ligament is rare. Owing to the absence of typical clinical signs and imaging methods, preoperative diagnosis is challenging, and it is mainly diagnosed through surgical pathology. PATIENT CONCERNS: The pa…

RATIONALE: Ovarian cystic tumors are common in adult women. However, cases of ovarian cystic tumors approximately 30 cm in diameter are rarely reported in adult women and even rarer in children. Here, we report a rare case of a giant ovaria…

Long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and retinopathy are 2 distinct yet interconnected areas of research in the field of ocular studies. MALAT1, with its diverse biological functions, h…

RATIONALE: Appendiceal mucinous tumors with intussusception are extremely rare. As primary lesions, malignant tumors often present with atypical clinical symptoms, which increases the likelihood of misdiagnosis. PATIENT CONCERNS: A 79-year…