Medicine

Primary dysmenorrhea (PDM) is highly prevalent among reproductive-aged women and is commonly managed with nonsteroidal anti-inflammatory drugs (NSAIDs), although medication-related adverse events and incomplete symptom control remain clinic…

The relationship between dietary patterns aligned with the EAT-Lancet reference diet, which promotes both human and planetary health, and female infertility remains unexplored. This study aimed to investigate the association between adheren…

This study aims to investigate the effects of different transfer strategies (blastocyst vs cleavage-stage embryo) on the cumulative live birth rate (CLBR) and perinatal outcomes. In this propensity score matching (PSM) study, we evaluated t…

Endometriosis and menorrhagia are prevalent gynecological conditions with overlapping symptoms, yet comparative data from Middle Eastern populations remain scarce. We aimed to comprehensively characterize demographic and hematological diffe…

Early-stage endometrial cancer frequently shares overlapping clinical presentations and sonographic features with benign endometrial disorders, making early detection challenging. This retrospective study evaluated clinical characteristics,…

Endometriosis (EMS) is a chronic condition primarily characterized by pain and infertility, significantly affecting the physical, mental, and emotional well-being of patients. The primary goal of EMS treatment is to improve patients' qualit…

This study aimed to construct and validate a nomogram for predicting natural pregnancy after hysteroscopy and laparoscopy in patients with tubal infertility and pelvic endometriosis, providing a basis for precise clinical evaluation and per…

This study aims to investigate the differences in response to dienogest (DNG) therapy among patients with 3 different phenotypes of endometriosis: ovarian endometrioma (OMA), superficial peritoneal endometriosis (SUP), and deep infiltrating…

Coccydynia is a chronic pain syndrome with a complex pathophysiology. While ganglion impar blockade (GIB) is an effective treatment, predictors of response are not well-established. This study aimed to evaluate whether hematologic inflammat…

Uterine cancer (UC) is the most common malignancy of the female reproductive system worldwide, with a continuously rising incidence, posing a significant public health challenge. This study systematically evaluated the burden of UC using th…

Endometriosis is a chronic inflammatory disease that can cause many problems such as dipmenorrhea, dyspareunia, pelvic pain, and infertility. The aim of this study was to investigate the clinical, demographic, and laboratory characteristics…

Endocrine disrupting chemicals (EDCs) have been associated with disorders affecting female reproductive health, although the precise causal connections and underlying pathways between these substances and such disorders remain incompletely …

INTRODUCTION: Diminished ovarian reserve (DOR) refers to a decrease in the quantity and/or quality of oocytes in the ovaries, resulting in decreased fertility. DOR is one of the primary causes of infertility in women. Electroacupuncture the…

BACKGROUND: Endometrial carcinoma arising from adenomyosis (EC-AIA) is remarkably uncommon, and its underlying molecular mechanisms are not yet fully elucidated. This knowledge gap is particularly significant given that most reported EC-AIA…

Ectopic pregnancy (EP) remains a major cause of early pregnancy-related morbidity and mortality. It can significantly impact future fertility and is associated with various risk factors. To investigate the incidence, clinical profile, and r…

Earlier examinations of how risk factors relate to endometriosis (EMT) have largely depended on observational designs, which arrived at conflicting conclusions. The present approach seeks to probe the causal association between 108 traits a…

Leuprolide and Goserelin, both gonadotropin-releasing hormone (GnRH) agonists, are commonly used for ovarian function suppression and the management of hormone-dependent cancers. However, systematic comparisons of their adverse event (AE) p…

This study aims to evaluate the diagnostic accuracy of the Pipelle biopsy based on sensitivity and specificity in women with abnormal uterine bleeding. This retrospective observational study included women who reported abnormal uterine blee…

Early identification of patients at risk for severe acute pancreatitis (AP) remains a major clinical challenge. Although several clinical scores and inflammatory markers are used for risk stratification, their predictive performance is vari…

This study aims to elucidate the molecular mechanisms underlying luteolin's therapeutic effects on polycystic ovary syndrome (PCOS) and endometriosis (EM), thereby providing a theoretical foundation for developing novel treatment strategies…

Dyslipidaemia is related to endometriosis, but it is not known which lipid component is most relevant, and whether the observed correlation reflects the causal relationship. The relationship between triglycerides (TG) and endometriosis is s…

Chronic pelvic pain is a common and multifactorial clinical syndrome that markedly impairs quality of life in both men and women. Superior hypogastric plexus block (SHGPB) is an effective minimally invasive treatment. The sacral notch appro…

Patients with acute pancreatitis (AP) in the intensive care unit experience high complication and mortality rates, making early prognosis prediction crucial. While the aspartate aminotransferase to alanine aminotransferase (AST/ALT) ratio i…

Accumulating observational evidence suggests an association between thyroid function and endometriosis, though the causal relationship remains unclear. To investigate potential bidirectional causal relationships, including for endometriosis…

Ovarian cancer is one of the most lethal gynecological malignancies globally, with significant variations in incidence, prevalence, and outcomes across regions and population subgroups. This study systematically evaluates the global, region…