Extracellular vesicles and circulating nucleic acids

Aim: A balanced uterine environment is crucial for the positive outcome of a pregnancy. Any alteration of its physiological status could affect embryo-maternal crosstalk and impair the mare fertility, as occurs in endometrial inflammatory c…

Ovarian cancer is one of the leading causes of gynecologic cancer-related mortality in women. However, a significant proportion of ovarian cancer cases are only detected at an advanced stage (III or IV) and are complicated to treat because …

Aim: Endometriosis is a chronic inflammatory disorder requiring clinical examination, imaging, and surgical intervention for accurate assessment. The aim of the present study was to provide a detailed biophysical and biochemical characteriz…

Aim: Acute pancreatitis (AP) is an inflammatory disorder of the pancreas lacking specific therapy and frequently complicated by oxidative stress (OS) and long-term endocrine dysfunction, including pancreatogenic diabetes. Pomegranate-derive…

Cell-to-cell communication is believed to be facilitated by membrane-bound vesicles called extracellular vesicles (EVs), which are released by cells. Protein, lipids, and nucleic acids are major cargo of EVs and are transported in these ves…

Extracellular vesicles (EVs) are small, lipid-bound packages that are secreted by all cell types and have been implicated in many diseases, such as cancer and neurodegenerative disorders. Though limited, an exciting new area of EV research …