Current drug safety

· 2 papers in corpus

meta-analysis 2013

Use of insulin and insulin analogs and risk of cancer - systematic review and meta-analysis of observational studies

doi:10.2174/15680266113136660067 ·PMID:24215311

BACKGROUND: An association of insulin use and risk of cancer has been reported but evidence is conflicting and methodological issues have been identified. OBJECTIVE: To summarize results regarding insulin use and cancer risk by a systemati…

lab-animal 2010

Fukinolic acid derivatives and triterpene glycosides from black cohosh inhibit CYP isozymes, but are not cytotoxic to Hep-G2 cells in vitro

doi:10.2174/157488610790936150 ·PMID:20406160

Black cohosh (Actaea racemosa L. [syn. Cimifuga racemosa L.]) extracts (BCE) are marketed worldwide for the management of menopausal symptoms. However, recently more than 75 cases of hepatotoxicity associated with black cohosh ingestion hav…