Archives of biochemistry and biophysics

Arch Biochem Biophys · ISSN (e) 1096-0384 · 3 papers in corpus
article 2025
Mechanism of vascular endothelial growth factor regulating hypoxia and inflammatory microenvironment in endometriosis: based on bioinformatics and multi-level validation
doi:10.1016/j.abb.2025.110639 ·PMID:41077175

Endometriosis remains a prevalent gynecological disorder that affects women during their reproductive years, featured by progressive inflammation and enhanced HIF-1α expression. This paper intended to plumb the mechanism of vascular endothe…

article 2025
Therapeutic effects and mechanisms of alcohol extracts from Polygala fallax Hemsl on endometriosis in rats
doi:10.1016/j.abb.2025.110393 ·PMID:40090438

Endometriosis is a chronic estrogen-dependent inflammatory disease that significantly affects women's health. Polygala fallax Hemsl. (PFH), a traditional Zhuang medicine, has been frequently used for gynecological disorders. This study inve…

article 2024
Concurrent detection of the mitochondrial DNA copy number and the +35G/C polymorphism in the mitochondrial transcription factor A gene in endometriosis
doi:10.1016/j.abb.2024.110152 ·PMID:39265693

BACKGROUND AND AIM: Endometriosis is a chronic gynecological inflammatory disease. The mitochondrial DNA copy number (mtDNA CN) and mitochondrial transcription factor A (TFAM) are known to contribute to human pathologies and cancer. Therefo…