Pharmacogenomics and personalized medicine

Pharmgenomics Pers Med · ISSN (print) 1178-7066 · 5 papers in corpus
2024
doi:10.2147/pgpm.s449101 ·PMID:38979513

Recent research findings have highlighted the pivotal roles played by lncRNAs in both normal human development and disease pathogenesis. LncRNAs are expressed in oocytes and early embryos, and their expression levels change dynamically once…

other 2022
doi:10.2147/PGPM.S354957 ·PMID:35496348

BACKGROUND: Endometriosis (EMS) is a common and highly recurrent gynecological disease characterized by chronic pain and infertility. There are no definitive therapies for endometriosis since the pathogenesis remains undetermined. This stud…

2022
doi:10.2147/pgpm.s345772 ·PMID:35418772

BackgroundEndometrial carcinoma (EC) is one of the most common malignant gynecological malignancies. BCL11A gene may have a tumor-suppressor role in EC. Until now, no studies have reported the effect of BCL11A variants on EC predisposition …

2020
doi:10.2147/pgpm.s265730 ·PMID:32848443

BackgroundHirschsprung disease (HSCR) is a rare congenital gastrointestinal disease characterized by the absence of intestinal submucosal and myometrial ganglion cells. Recently, researches indicated that miR-100 regulated the growth, diffe…

2019
doi:10.2147/pgpm.s230751 ·PMID:31849513

BackgroundExisting drugs are far from enough for investigators and patients to administrate the therapy of rheumatoid arthritis. Drug repositioning has drawn broad attention by reusing marketed drugs and clinical candidates for new uses.Pur…