Biometrics

In application of diagnostic accuracy, it is possible that a priori information may exist regarding the test score distributions, either between different disease populations for a single test or between multiple correlated tests. Few have …

In diagnostic medicine, estimating the diagnostic accuracy of a group of raters or medical tests relative to the gold standard is often the primary goal. When a gold standard is absent, latent class models where the unknown gold standard te…

In this article, we consider comparing the areas under correlated receiver operating characteristic (ROC) curves of diagnostic biomarkers whose measurements are subject to a limit of detection (LOD), a source of measurement error from instr…