Gynecologic oncology reports

OBJECTIVE: To evaluate the association of abdominal wall blocks at the time of robotic hysterectomy performed for endometrial cancer (EC) with in-hospital post-operative opioids. METHODS: We performed a retrospective cohort study of patien…

BACKGROUND: Extrauterine adenosarcomas are rare gynecologic malignancies that can arise within foci of pelvic endometriosis. They are often hormone mediated and thus are challenging to treat during pregnancy. CASE PRESENTATION: We present …

OBJECTIVE: To evaluate self-reported adverse childhood experiences (ACEs) in patients with endometrial cancer and class 3 obesity undergoing a preoperative weight loss protocol, and summarize the existing literature surrounding ACEs, endome…

BACKGROUND: Primary vulvar adenocarcinoma of mammary gland type (AMGT) is a rare gynecologic cancer with only 54 reported cases to date. The tumor may have variety of histologic patterns and can be confused with other more common entities o…

Gynecologic neuroendocrine carcinoma (NEC) is a rare and aggressive malignancy with limited treatment options and poor prognosis. Homologous recombination deficiency (HRD) is an established predictive biomarker for poly(ADP-ribose) polymera…

INTRODUCTION: Ovarian clear cell carcinoma (OCCC) is a rare and aggressive histologic subtype of epithelial ovarian cancer characterized by intrinsic chemoresistance and limited treatment options in the platinum-resistant setting. Immune ch…

BACKGROUND: Uterine smooth muscle tumors of uncertain malignant potential (STUMPs) are rare tumors that share features with benign leiomyomas and malignant leiomyosarcomas. The standard treatment is a total hysterectomy for those without in…

Intraoperative pathology consultations play an important role in surgical management of oncologic patients. The benefits of frozen section, and cytologic samples are well known and studied. We reviewed the literature and describe a case tha…

BACKGROUND: Paget's disease (EMPD) of the vulva primarily affects postmenopausal women and can present significant challenges in early clinical detection.Case Presentation: We report an exceedingly rare case of invasive acantholytic extrama…

OBJECTIVE: To contextualize two institutional cases of Bartholin gland adenoid cystic carcinoma with biopsy-confirmed distant metastases within the broader published literature and to delineate clinical, pathologic, and molecular patterns a…

OBJECTIVES: To present a rare case of mixed vaginal tumor with atypical features and to discuss clinical management in the context of uncertainty regarding biological behavior. METHODS: We present the clinical course of a 50-year-old woman…

BACKGROUND: Extranodal marginal zone lymphoma (EMZL) is a type of low-grade B-cell lymphoma that most commonly occurs in gastric tissue. To our knowledge, only five cases have been documented noting primary EMZL of the fallopian tube and on…

BACKGROUND: The differential diagnosis for a solid pelvic mass is broad and includes non-gynecologic masses such as retroperitoneal schwannoma. Theses benign nerve-sheath tumors can be mistaken for adnexal masses or cause non-specific bulk …

BACKGROUND: Epithelial ovarian cancer commonly presents with vague symptoms that delay diagnosis until disease is advanced. Granulomatous peritonitis is a term used to describe granulomatous inflammation within the peritoneal cavity and mim…

OBJECTIVE: Symptoms occur in up to 75% of patients with early-stage ovarian cancer; as such, using a symptom inventory (SI) to stratify which patients should receive screening for ovarian cancer is an attractive approach to mitigate false-p…

INTRODUCTION: Low-grade serous carcinoma (LGSC) is a rare, indolent subtype of epithelial ovarian cancer that often arises from precursor lesions in the ovary or peritoneum and is associated with MAPK pathway mutations. Unlike high-grade se…

Primary peritoneal serous borderline tumors (PPSBT) are epithelial proliferations with low malignant potential, but they are rare entities. Due to their rarity, PPSBTs are often misdiagnosed as undiagnosed diffuse primary ovarian carcinomas…

BACKGROUND: Low-grade endometrial stroma sarcoma is a very rare mesenchymal neoplasm, that is usually found inside the uterine corpus. It is very uncommon that LG-ESS arises from extrauterine foci. CASE PRESENTATION: We report the case of …

BACKGROUND: Malignant Brenner tumor (MBT) with extensive clear cell features mimicking an ovarian clear cell carcinoma (CCC) is exceedingly rare. This case report discusses the diagnostic challenges associated with this unusual histologic f…

BACKGROUND: The increasing number of organ transplant recipients has led to a rise in cancer diagnoses in this population. Kidney transplant recipients, in particular, have a two-to-four-fold higher risk of developing cancer due to immunosu…

Intravenous leiomyomatosis (IVL) is a benign smooth muscle growth originating in the uterus that extends into the lumen of venous or lymphatic vessels beyond the myoma. The tumour may enter the inferior vena cava (IVC) or the heart. For IVL…

BACKGROUND: Non-Bacterial Thrombotic Endocarditis (NBTE) is characterized by the formation of sterile vegetations on the heart valves, often due to an underlying hypercoagulable state in the setting of malignancy, inflammation, or autoimmun…

•Primary vaginal serous and borderline tumors can occur at the vaginal stump in hysterectomized women.•A large specimen obtained by tumor resection is needed for accurate pathological diagnosis of vaginal tumors.•Investigation of vaginal en…

INTRODUCTION: This study aimed to evaluate the prognostic significance of CT-based Peritoneal Cancer Index (CT-PCI) scores and serum CA-125 levels, assessed before and after neoadjuvant chemotherapy (NACT), in relation to surgical outcomes …

INTRODUCTION: Pseudo-Meigs' syndrome is a rare condition described as the presentation of a pleural effusion and ascites in the setting of a malignant pelvic mass that is not included in the definition of Meigs' syndrome, and which resolves…