F&S science

F S Sci · ISSN (e) 2666-335X · 55 papers in corpus
other 2020
Decreased gremlin 1 expression in women with BMI ≥35 kg/m2 is mediated by interleukin 10 and interleukin 1β in the follicular fluid
doi:10.1016/j.xfss.2020.06.003 ·PMID:34296200

OBJECTIVE: To determine how body mass index (BMI) affects the follicular fluid cytokine milieu and investigate how this inflammatory environment impacts cumulus signaling. DESIGN: Experimental study. SETTING: Tertiary hospital based resea…

lab-animal 2020
Establishment and characterization of cell lines from human endometrial epithelial and mesenchymal cells from patients with endometriosis
doi:10.1016/j.xfss.2020.09.001 ·PMID:35559928

OBJECTIVE: To establish and characterize cell lines derived from human endometrial epithelial cells (ECs) and mesenchymal cells (MCs) from patients with and without endometriosis. DESIGN: In vitro experimental study. SETTING: University a…

lab-animal 2020
Genome-wide estrogen receptor-α binding and action in human endometrial stromal cells
doi:10.1016/j.xfss.2020.06.002 ·PMID:35559740

OBJECTIVE: To investigate the gene targets of estradiol (E2)-estrogen receptor-α (ESR1) in human endometrial stromal cells. DESIGN: Basic science. SETTING: University research center. PATIENT(S): Premenopausal women with or without endom…

other 2020
Mild hyperandrogenemia in presence/absence of a high-fat, Western-style diet alters secretory phase endometrial transcriptome in nonhuman primates
doi:10.1016/j.xfss.2020.08.003 ·PMID:33554152

OBJECTIVE: To identify novel transcriptomic changes to eutopic endometrium by exposure to chronic mild hypernadrogenemia (testosterone [T]) with/without exposure to an obesogenic Western-style diet (WSD). DESIGN: Two-by-two factorial arran…

observational 2020
Pretreatment with a gonadotropin-releasing hormone agonist and an aromatase inhibitor may improve outcomes in in vitro fertilization cycles of women with stage I-II endometriosis
doi:10.1016/j.xfss.2020.06.005 ·PMID:35559744

OBJECTIVE: To determine whether 2 months of pretreatment with 5 mg of letrozole daily plus leuprolide acetate at 3.75 mg monthly in women with laparoscopically confirmed American Society of Reproductive Medicine stage I-II endometriosis imp…