Clinical chemistry and laboratory medicine

Clin Chem Lab Med · ISSN (print) 1434-6621 · 7 papers in corpus
article 2021
doi:10.1515/cclm-2021-0510 ·PMID:34388324

OBJECTIVES: To evaluate the impact of different biologic, histopathologic and lifestyle factors on serum levels of human epididymis protein 4 (HE4) and Cancer antigen 125 (CA125) in the diagnostic work up of women with an ovarian cyst or pe…

letter 2017
doi:10.1515/cclm-2017-0016 ·PMID:28453438

Introduction: Endometriosis is a chronic disease often associated with pelvic pain and infertility. It has been shown that vitamin D plays an important role in the physiological functions of the reproductive system. Conflicting data have be…

article 2013
doi:10.1515/cclm-2013-0151 ·PMID:24013103

BACKGROUND: Human epididymis protein 4 (HE4), kallikrein 6 (KLK6), osteopontin (OPN) and soluble mesothelin-related peptide (SMRP) are new promising biomarkers that could integrate CA125 in epithelial ovarian cancer (EOC) diagnosis. The aut…

article 2011
doi:10.1515/cclm.2011.709 ·PMID:21923475

BACKGROUND: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy. METHODS: We retro…

other 2009
doi:10.1515/CCLM.2009.134 ·PMID:19317653

BACKGROUND: The aim of this study was to assess the prognostic value of cancer antigen (CA) 125 and CA 72-4 in patients with ovarian borderline tumor (BOT). METHODS: All women diagnosed and treated for BOT at our institution between 1981 a…

2005
doi:10.1515/cclm.2005.238 ·PMID:16309379

Matrix metalloproteinases are a family of zinc-dependent proteinases which are involved in the breakdown and remodeling of extracellular matrix. As children grow and adolescents reach pubescence, their bodies undergo changes that require ag…

article 2004
doi:10.1515/cclm.2004.102 ·PMID:15259373

Autoinflammatory phenomena, including autoantibody production and atopy, have been regarded as associated with endometriosis. The present study investigates the activity of eosinophils and the distribution of immunoglobulin E concentrations…