Peptides

Peptides · ISSN (e) 1873-5169 · 3 papers in corpus
article 2024
R-954, a bradykinin B1 receptor antagonist, as a potential therapy in a preclinical endometriosis model
doi:10.1016/j.peptides.2024.171294 ·PMID:39265809

Endometriosis is a gynecological condition characterized by the growth of endometrium-like tissues outside of the uterine cavity. Currently available drugs are efficacious in treating endometriosis-related pain, however it's not a targeted …

review 2015
Peptides: Basic determinants of reproductive functions
doi:10.1016/j.peptides.2015.05.016 ·PMID:26074346

Mammalian reproduction is a costly process in terms of energy consumption. The critical information regarding metabolic status is signaled to the hypothalamus mainly through peripheral peptides from the adipose tissue and gastrointestinal t…

2012
Expression of corticotropin releasing factor receptor type 1 (CRF1) in the human gastrointestinal tract and upregulation in the colonic mucosa in patients with ulcerative colitis.
doi:10.1016/j.peptides.2012.07.028 ·PMID:22948128

Brain corticotropin-releasing factor (CRF) acting on CRF receptor type 1 (CRF(1)) is a main signaling pathway in the stress response. CRF is also produced in a variety of peripheral sites and acts locally as a proinflammatory mediator. We i…