Breast cancer (Tokyo, Japan)

2025

Emerging roles of KIR2DL4 in cancer immunotherapy.

doi:10.1007/s12282-025-01738-y ·PMID:40549069

Killer-cell immunoglobulin-like receptor 2DL4 (KIR2DL4), a member of the killer cell immunoglobulin-like receptors (KIRs) family, plays an important role in the regulation of the immune system, which is expressed primarily on natural killer…

2017

Atypical femoral fracture after receiving antiresorptive drugs in breast cancer patients with bone metastasis.

doi:10.1007/s12282-016-0746-8 ·PMID:27943163

BackgroundAtypical femoral fracture (AFF) occurs with minor trauma in patients receiving antiresorptive drugs such as bisphosphonate and denosumab. We hypothesized that patients with bone metastasis who receive higher doses of antiresorptiv…

2016

A randomized controlled study evaluating safety and efficacy of leuprorelin acetate every-3-months depot for 2 versus 3 or more years with tamoxifen for 5 years as adjuvant treatment in premenopausal patients with endocrine-responsive breast cancer.

doi:10.1007/s12282-015-0593-z ·PMID:25655898

BackgroundLuteinizing hormone-releasing hormone (LH-RH) agonists provide effective adjuvant treatment for premenopausal women with endocrine-responsive breast cancer. Here, we investigated appropriate treatment durations of an LH-RH agonist…