Fertility and sterility

OBJECTIVE: To evaluate the effect of luteal phase support (LPS) in intrauterine insemination (IUI) cycles stimulated with gonadotropins. DESIGN: Randomized multicenter trial. SETTING: Academic tertiary care centers and affiliated secondar…

The immune system plays a critical role in pregnancy establishment and maintenance, but application of immunological principles to the treatment of infertility and pregnancy loss has had a checkered past. Improving knowledge in this area ho…

OBJECTIVE: To report our three surgical approaches in the management of diaphragmatic endometriosis. DESIGN: Video article presenting laparoscopic surgical techniques, with and without robotic assistance. SETTING: University hospital. PA…

Significant progress has been made in the understanding of embryonic competence and endometrial receptivity since the inception of assisted reproductive technology. The endometrium is a highly dynamic tissue that plays a crucial role in the…

OBJECTIVE: To show characteristics of deeply infiltrative endometriosis (DIE) on magnetic resonance imaging (MRI) and how they correlate with intraoperative findings. DESIGN: Overview of still and dynamic MRI images of four different patie…

Our objective was to define and propose a standardized magnetic resonance (MR) imaging structured report in patients with infertility to have clinical completeness on possible diagnosis and severity. Patients should be studied preferable on…

OBJECTIVE: To evaluate the relationship between pretreatment intake of whole grains and outcomes of IVF. DESIGN: Prospective cohort study. SETTING: Academic medical center. PATIENT(S): A total of 273 women who collectively underwent 438 …

ObjectiveTo characterize normative antimüllerian hormone (AMH) levels and ascertain which factors are associated with AMH in a large cohort of reproductive-age women.DesignCross-sectional study.SettingNot applicable.Patient(s)A total of 1,6…

The authors review aberrations of uterine anatomy and physiology affecting pregnancy outcomes with IVF. In the case of endometriosis and hydrosalpinx, pathologies outside of the uterus alter the uterine endometrium. In the case of endometri…

OBJECTIVE: To assess the characteristics of IVF cycles for which preimplantation genetic diagnosis (PGD) was used and to evaluate indications for PGD and treatment outcomes associated with this procedure as compared with cycles without PGD …

Endometriosis is a disorder associated with a general inflammatory response in the peritoneal cavity. Oxidative stress is a potential factor involved in the pathophysiology of this disease, and reactive oxygen species (ROS) are implicated i…

OBJECTIVE: To evaluate potential variations in the plasma metabolomic profile of endometriosis patients as a consequence of pathophysiologic alterations associated with this disorder. DESIGN: Prospective study. For each subject, a plasma s…

OBJECTIVE: To investigate the possible correlation between maternal characteristics, in utero and early neonatal life exposures, and the development of endometriosis in adult life. DESIGN: Case-control study. SETTING: University hospital.…

OBJECTIVE: To evaluate the impact of an episode of intermenstrual bleeding on the probability of conception in a menstrual cycle (fecundability). DESIGN: Prospective, time-to-pregnancy cohort study. SETTING: Community-based cohort. PATIE…

OBJECTIVE: To report postoperative outcomes after rectal shaving for deep endometriosis infiltrating the rectum. DESIGN: Retrospective study using data prospectively recorded in the CIRENDO database. SETTING: University tertiary referral …

OBJECTIVE: To report the medical and surgical management of a rare case of recurrent moss-like endometriosis and associated hemorrhagic ascites. DESIGN: Video description of the case, demonstration of the surgical technique, discussion of …

OBJECTIVE: To evaluate whether women with endometriosis achieving singleton pregnancies with IVF face an increased risk of miscarriage. DESIGN: Matched case-control study. SETTING: Infertility units. PATIENT(S): Women achieving singleton…

OBJECTIVE: To study possible associations among endometriosis, pelvic infectious disease, and ART. DESIGN: Retrospective cohort analysis over 4 consecutive years, based on medical records and insurance coding in a tertiary endometriosis re…

A surgical trauma results within minutes in exudation, platelets, and fibrin deposition. Within hours, the denuded area is covered by tissue repair cells/macrophages, starting a cascade of events. Epithelial repair starts on day 1 and is te…

OBJECTIVE: To investigate serum microRNAs (miRNAs) in women with endometriosis. DESIGN: Case-control study. SETTING: University hospital. PATIENT(S): Women with (n = 24) and without (n = 24) endometriosis. INTERVENTION(S): Serum samples…

OBJECTIVE: To evaluate existing evidence of a possible association in women with endometriosis between controlled ovarian hyperstimulation plus embryo transfer (COH-ET) and the occurrence of spontaneous hemoperitoneum in pregnancy (SHiP). …

OBJECTIVE: To determine expression of stanniocalcin-1 (STC1) in human endometrium with and without endometriosis and its regulation by steroid hormones. DESIGN: Laboratory study. SETTING: University. PATIENT(S): Nineteen women with endom…

OBJECTIVE: To study national-level trends in assisted reproduction technology (ART) treatments and outcomes as well as the characteristics of women who have sought this form of infertility treatment. DESIGN: Population-based study. SETTIN…

OBJECTIVE: To determine the impact of endometriotic lesion removal on local and systemic inflammation. DESIGN: Multiplex cytokine analysis on samples from endometriosis patients before surgery, 2 weeks after surgery, and 3 months after sur…