Analytical and bioanalytical chemistry

Anal Bioanal Chem · ISSN (e) 1618-2650 · 9 papers in corpus
review 2025
doi:10.1007/s00216-025-06196-1 ·PMID:41240084

MicroRNAs (miRNAs) have emerged as robust biomarkers for diagnosing and prognosing gynecological diseases due to their disease-specific expression and remarkable stability in body fluids. Despite the inherent instability of RNA molecules, c…

article 2025
doi:10.1007/s00216-025-05930-z ·PMID:40533635

Endometriosis is a gynecological condition characterized by the uncontrolled growth of endometrial-like tissue outside the uterine cavity. Although highly prevalent, the biological mechanisms of endometriosis are poorly understood, and the …

2024
doi:10.1007/s00216-024-05275-z ·PMID:38584178

Multiplexed lateral flow assays (LFAs) offer efficient on-site testing by simultaneously detecting multiple biomarkers from a single sample, reducing costs. In cancer diagnostics, where biomarkers can lack specificity, multiparameter detect…

2023
doi:10.1007/s00216-023-04522-z ·PMID:36645457

Since its discovery in 2007, polydopamine nanofilms have been widely used in many areas for surface functionalization. The simple and low-cost preparation method of the nanofilms with tunable thickness can incorporate amine and oxygen-rich …

2022
doi:10.1007/s00216-022-03881-3 ·PMID:35043262

We developed and validated a liquid chromatography high-resolution mass spectrometry method for the absolute quantification of 51 steroids for clinical analysis of human serum and, for the first time, peritoneal fluid. Data acquisition was …

2022
doi:10.1007/s00216-022-04293-z ·PMID:36063171

Gonadotropin-releasing hormone isoform I (GnRH), a neuro-deca-peptide, plays a fundamental role in development and maintenance of the reproductive system in vertebrates. The anomalous release of GnRH is observed in reproductive disorder suc…

2021
doi:10.1007/s00216-020-03045-1 ·PMID:33242117

Biofluids, such as blood plasma or serum, are currently being evaluated for cancer detection using vibrational spectroscopy. These fluids contain information of key biomolecules, such as proteins, lipids, carbohydrates and nucleic acids, th…

2021
doi:10.1007/s00216-021-03472-8 ·PMID:34195877

Ovarian cancer remains the most lethal gynaecological malignancy, as its timely detection at early stages remains elusive. Attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy of biofluids has been previously appli…

2018
doi:10.1007/s00216-018-1111-x ·PMID:29740671

The cyclical process of regeneration of the endometrium suggests that it may contain a cell population that can provide daughter cells with high proliferative potential. These cell lineages are clinically significant as they may represent c…