BMC genomic data

BMC Genom Data · ISSN (e) 2730-6844 · 3 papers in corpus
2024
Prediction of the most deleterious non-synonymous SNPs in the human IL1B gene: evidence from bioinformatics analyses.
doi:10.1186/s12863-024-01233-x ·PMID:38858637

BackgroundPolymorphisms in IL1B play a significant role in depression, multiple inflammatory-associated disorders, and susceptibility to infection. Functional non-synonymous SNPs (nsSNPs) result in changes in the encoded amino acids, potent…

article 2022
Bioinformatical analysis of the key differentially expressed genes and associations with immune cell infiltration in development of endometriosis
doi:10.1186/s12863-022-01036-y ·PMID:35303800

Abstract Background This study explored the key genes related to immune cell infiltration in endometriosis. Results The Gene Expression Omnibus (GEO) datasets (GSE7305, GSE7307, and GSE11691), containing a total of 37 endometriosis and 42 n…

2022
Mitochondria in tumour progression: a network of mtDNA variants in different types of cancer.
doi:10.1186/s12863-022-01032-2 ·PMID:35183124

BackgroundMitochondrial participation in tumorigenesis and metastasis has been studied for many years, but several aspects of this mechanism remain unclear, such as the association of mitochondrial DNA (mtDNA) with different cancers. Here, …