Current research in pharmacology and drug discovery

· 2 papers in corpus

2023

Recent advancements of miRNAs in the treatment of bone diseases and their delivery potential.

doi:10.1016/j.crphar.2022.100150 ·PMID:36691422

Advances in understanding miRNAs as endogenous posttranscriptional regulatory units have projected them as novel therapeutics for several untreatable diseases. miRNAs are endogenous non-coding small single-stranded RNA molecules (20-24 nucl…

2022

Choline chloride attenuates the allergic airway disease by inhibiting the lysophosphatidylcholine induced response in mouse model.

doi:10.1016/j.crphar.2022.100109 ·PMID:35707627

AimsAllergic airway disease manifestation is induced by lysophosphatidylcholine (LPC) through CD1d-restricted Natural killer T (NKT) cells. Choline chloride (ChCl) and LPC both have the "choline" moiety in their structure and this may inter…