Journal of medical case reports

J Med Case Rep · ISSN (e) 1752-1947 · 146 papers in corpus
review 2026
doi:10.1186/s13256-026-05914-2 ·PMID:42063071

BACKGROUND: Endosalpingiosis is a rare benign condition characterized by the ectopic presence of ciliated tub epithelium outside the fallopian tubes, often found in the ovaries, uterus, and other pelvic structures. CASE PRESENTATION: This …

case-report 2026
doi:10.1186/s13256-026-06062-3 ·PMID:42035203

BACKGROUND: Primary hyperparathyroidism (PHPT) and familial hypocalciuric hypercalcemia (FHH) are key differential diagnoses in parathyroid hormone (PTH)-mediated hypercalcemia. While PHPT often arises from single-gland parathyroid adenomas…

case-report 2026
doi:10.1186/s13256-026-05947-7 ·PMID:41782157

BACKGROUND: Hemorrhagic ascites is a rare manifestation of endometriosis. Here, we present an unusual case in a perimenopausal woman that was successfully managed laparoscopically, and summarize its clinical characteristics to provide guida…

case-report 2026
doi:10.1186/s13256-026-05910-6 ·PMID:41761345

BACKGROUND: Genital tuberculosis affecting prepubertal girls is extremely uncommon, posing a great diagnostic challenge. It is a form of extrapulmonary tuberculosis usually seen in the reproductive age group. It can lead to significant heal…

case-report 2026
doi:10.1186/s13256-025-05772-4 ·PMID:41917958

BACKGROUND: Rosai Dorfman disease is a rare histiocytosis, which is characterized by accumulation of histiocytes in lymph nodes, but also in extranodal locations. Histologically, one of the key features of Rosai Dorfman disease is emperipol…

case-report 2026
doi:10.1186/s13256-026-05975-3 ·PMID:41864969

BACKGROUND: Abdominal pregnancy refers to the implantation of a fertilized egg in the abdominal cavity outside of the uterus, fallopian tubes, and ovaries; splenic pregnancy is a rare type of abdominal pregnancy. CASE PRESENTATION: Our pat…

review 2026
doi:10.1186/s13256-026-06064-1 ·PMID:42106852

BACKGROUND: Malignant Brenner tumor (MBT) is a rare ovarian neoplasm with unpredictable behavior, posing significant diagnostic and therapeutic challenges. Current management advocates for risk-adapted strategies, though long-term outcome d…

review 2026
doi:10.1186/s13256-026-06083-y ·PMID:42121256

BACKGROUND: The Sister Mary Joseph's nodule (SMJN) is an umbilical skin metastasis observed in the advanced stages of abdominopelvic malignancies. It is rare and is typically associated with a poor prognosis. The appearance of the skin lesi…

case-report 2026
doi:10.1186/s13256-026-06317-z ·PMID:42393804

BACKGROUND: Peritoneal defects of the broad ligament of the uterus are uncommon anatomical abnormalities that may be congenital or acquired. Situs inversus totalis is a congenital condition characterized by a complete mirror-image arrangeme…

case-report 2026
doi:10.1186/s13256-026-05845-y ·PMID:41652477

BACKGROUND: Spontaneous rupture of the uterus during the early weeks of gestation is rare. When it occurs, it is a life-threatening obstetric emergency. Most uterine ruptures happen in scarred uteri and during the late third trimester. This…

case-report 2026
doi:10.1186/s13256-026-05989-x ·PMID:41918028

BACKGROUND: Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare (prevalence ~ 1:2 million), devastating genetic disorder characterized by progressive heterotopic ossification. Crucially, surgical trauma is a potent trigger for cata…

case-report 2026
doi:10.1186/s13256-026-05907-1 ·PMID:41803932

BACKGROUND: Adenomyosis negatively impacts fertility treatment outcomes by lowering clinical pregnancy rates, reducing live birth rates, and increasing miscarriage rates following in vitro fertilization. Hormonal suppression therapy has eme…

case-report 2026
doi:10.1186/s13256-026-05831-4 ·PMID:41566342

BACKGROUND: Thoracic endometriosis syndrome is an uncommon condition defined by the existence of functional endometrial tissue outside of the uterine cavity, specifically in the pleura, lung parenchyma, or airways. We present a case report …

case-report 2026
doi:10.1186/s13256-026-06150-4 ·PMID:42289750

BACKGROUND: Endometriosis is a common gynecologic condition, but extra-pelvic manifestations are rare and often pose significant diagnostic challenges. Thoracic and abdominal endometriosis may present with nonspecific respiratory and abdomi…

case-report 2026
doi:10.1186/s13256-026-05833-2 ·PMID:41593759

BACKGROUND: Undifferentiated endometrial carcinoma is a solid tumor that originates from endometrial epithelial cells, accounting for approximately 9% of endometrial cancers. Undifferentiated endometrial carcinoma exhibits high invasiveness…

case-report 2025
doi:10.1186/s13256-025-05301-3 ·PMID:40390083

BACKGROUND: Endometriosis affects 6-15% of reproductive-aged women, with abdominal wall endometriosis occurring in 1-12% of extrapelvic cases. Cesarean scar endometriosis, the most common abdominal wall endometriosis subtype, arises in 0.03…

case-report 2025
doi:10.1186/s13256-025-05669-2 ·PMID:41250141

BACKGROUND: Adnexal masses represent a prevalent gynecological condition that may affect females of any age, although particularly those of reproductive age. These masses can be classified as either physiological or neoplastic, with the maj…

case-report 2025
doi:10.1186/s13256-025-05337-5 ·PMID:40537844

BACKGROUND: Endometriosis is defined as the presence of functional glands and stroma of the uterus outside its cavity. It affects 10-20% of women of reproductive age. It can form in different parts of the body; the involvement of the urinar…

review 2025
doi:10.1186/s13256-025-05441-6 ·PMID:41225508

BACKGROUND: Clear cell carcinoma of the colon is a rare entity in colon malignancy. All of the cases involving primary colon clear cell carcinoma are case studies. Since clear cell component can be seen in colon metastasis, adenocarcinoma, …

case-report 2025
doi:10.1186/s13256-025-05384-y ·PMID:40616185

BACKGROUND: Uterine leiomyomas (uterine fibroids) are the most common tumors of the uterus. Extrauterine fibroids are rare, with the broad ligament being the most common location. Fibroids are usually asymptomatic. Some common symptoms incl…

case-report 2025
doi:10.1186/s13256-025-05043-2 ·PMID:39833927

BACKGROUND: Heterotaxia is characterized by an abnormal positioning of the thoracic and/or abdominal organs, resulting in various physiological and hemodynamic implications. Congenital heart disease involves structural irregularities in the…

case-report 2025
doi:10.1186/s13256-025-05448-z ·PMID:40999470

BACKGROUND: High-grade endometrial stromal sarcoma is a rare and aggressive subtype of uterine sarcoma, characterized by a poor prognosis. While typical initial manifestations include gynecological symptoms such as abnormal vaginal bleeding…

case-report 2025
doi:10.1186/s13256-025-05640-1 ·PMID:41194201

BACKGROUND: High-intensity focused ultrasound ablation has emerged as a noninvasive therapeutic option for adenomyosis of the uterus. We studied a female with infertility patient to explore the application of in vitro fertilization combined…

review 2025
doi:10.1186/s13256-025-05360-6 ·PMID:40611306

BACKGROUND: Abdominal ectopic pregnancy is a rare form of ectopic pregnancy, and diaphragmatic ectopic pregnancy is even rarer. We described a case of an ectopic pregnancy implanted on the diaphragm's surface, diagnosed using multimodality …

case-report 2025
doi:10.1186/s13256-025-05737-7 ·PMID:41408346

BACKGROUND: Traumatic separation of the cervix from the body of the uterus is exceedingly rare, particularly as a complication of pelvic fractures. This condition often poses significant diagnostic and therapeutic challenges, especially in …