BMJ open

BMJ Open · ISSN (e) 2044-6055 · 292 papers in corpus
other 2016
doi:10.1136/bmjopen-2016-013998 ·PMID:28003300

INTRODUCTION: Endometriosis is a common gynaecological disease characterised by pain and subfertility. Randomised controlled trials evaluating treatments for endometriosis have reported many different outcomes and outcome measures. This var…

meta-analysis 2016
doi:10.1136/bmjopen-2014-007224 ·PMID:26883234

OBJECTIVE: Surgical complications may affect patients psychologically due to challenges such as prolonged recovery or long-lasting disability. Psychological distress could further delay patients' recovery as stress delays wound healing and …

qualitative 2016
doi:10.1136/bmjopen-2016-014007 ·PMID:27940635

OBJECTIVE: To investigate young people's experiences of persistent musculoskeletal pain, including care needs and current service gaps as well as perceptions about the role of digital technologies to support their co-care. METHODS: A quali…

observational 2015
doi:10.1136/bmjopen-2014-006681 ·PMID:25735301

OBJECTIVES: The objective of this study was to evaluate the problem of multiple chronic conditions and polypharmacy in patients with fibromyalgia. DESIGN: Retrospective medical record review. SETTING: Olmsted County, Minnesota. PARTICIPA…

observational 2015
doi:10.1136/bmjopen-2015-007825 ·PMID:25783428

OBJECTIVE: To derive and validate a set of clinical risk prediction algorithm to estimate the 10-year risk of 11 common cancers. DESIGN: Prospective open cohort study using routinely collected data from 753 QResearch general practices in E…

observational 2015
doi:10.1136/bmjopen-2014-006360 ·PMID:25762230

OBJECTIVE: To classify diseases based on age at peak incidence to identify risk factors for later disease in women's life course. DESIGN: A cross-sectional baseline survey of participants in the Japan Nurses' Health Study. SETTING: A nati…

rct 2015
doi:10.1136/bmjopen-2015-008297 ·PMID:26141305

INTRODUCTION: The results of a recent meta-analysis showed that adding recombinant human luteinising hormone (r-hLH) to recombinant human follicle-stimulating hormone (r-hFSH) for ovarian stimulation was beneficial in poor responders, resul…

observational 2015
doi:10.1136/bmjopen-2015-007588 ·PMID:25979869

OBJECTIVE: To evaluate the awareness and response of fertility clinics in the UK to the National Institute for Health and Care Excellence (NICE) guideline recommendation that intrauterine insemination (IUI) should not be offered routinely, …

rct 2015
doi:10.1136/bmjopen-2015-008621 ·PMID:26576808

INTRODUCTION: Chronic pelvic pain (CPP) affects 3-4% of women worldwide. Proven treatments for CPP are limited and unsatisfactory. The meridian balance method (BM) electroacupuncture (EA) treatment (BMEA + Traditional Chinese Medicine Healt…

meta-analysis 2015
doi:10.1136/bmjopen-2015-009655 ·PMID:26656986

OBJECTIVES: To assess the quantity and quality of randomised, sham-controlled studies of surgery and invasive procedures and estimate the treatment-specific and non-specific effects of those procedures. DESIGN: Systematic review and meta-a…

rct 2014
doi:10.1136/bmjopen-2014-005986 ·PMID:25180056

INTRODUCTION: High levels of oxidative stress can have considerable impact on the outcomes of in vitro fertilisation (IVF). Recent studies have reported that melatonin, a neurohormone secreted from the pineal gland in response to darkness, …

observational 2014
doi:10.1136/bmjopen-2013-004197 ·PMID:24613821

OBJECTIVE: To determine the distribution of low birth weight (LBW), preterm birth, small for gestational age (SGA) and large for gestational age (LGA) by main cause of infertility (female, combined, male, unexplained) in women seeking infer…

observational 2014
doi:10.1136/bmjopen-2014-006447 ·PMID:25472658

OBJECTIVE: To identify risk factors for ovarian pregnancy (OP) and compare clinical features between OP and tubal pregnancy (TP) patients. DESIGN: Case-control study. SETTING: University hospital. PARTICIPANTS: A case-control study was c…

observational 2014
doi:10.1136/bmjopen-2013-003985 ·PMID:24384900

OBJECTIVES: This study aimed to assess the association of socioeconomic conditions with female fertility impairment among women who delivered a live birth. DESIGN: Cross-sectional analysis. SETTING: Population-based birth cohort (Generati…

meta-analysis 2014
doi:10.1136/bmjopen-2014-006325 ·PMID:25534211

OBJECTIVE: Since conflicting results have been published on the role of tobacco smoking on the risk of endometriosis, we provide an up-to-date summary quantification of this potential association. DESIGN: We performed a PubMed/MEDLINE sear…

rct 2014
doi:10.1136/bmjopen-2013-004421 ·PMID:24589827

OBJECTIVE: To evaluate the validity of self-reported hysterectomy against the gold standard of uterine visualisation using pelvic ultrasound. DESIGN: Prospective cohort study. SETTING: UK Collaborative Trial of Ovarian Cancer Screening (U…

other 2012
doi:10.1136/bmjopen-2012-001297 ·PMID:22685224

INTRODUCTION: Chronic pelvic pain (CPP) affects >1 million UK women. Annual healthcare costs are estimated at >£150 million. Proven interventions for CPP are limited, and treatment is often unsatisfactory. Gabapentin is increasingly prescri…