Journal of the American Association for Laboratory Animal Science : JAALAS

Endometriosis is defined as endometrial tissue outside of the uterus. It is a debilitating, complex, and underdiagnosed condition, impacting approximately 10%-15% of reproductive-aged women worldwide. Endometriosis is associated with chroni…

A female, research-naive, strain 13 guinea pig with no previous significant health history was noted to have a persistent vaginal discharge. On physical examination a soft mass was noted in the lower abdomen accompanied by a serosanguineous…

Improved animal models of endometriosis are needed to accurately represent the pathophysiology of human disease and identify new therapeutic targets that do not compromise fertility. There is tremendous heterogeneity among published rodent …

Providing effective contraception for nonhuman primates (NHP) is challenging. Deslorelin acetate is a commercially available gonadotropin-releasing hormone (GnRH) agonist that may provide a relatively noninvasive, long-lasting, and potentia…

Subcutaneous injection site reactions to sustained-release buprenorphine hydrochloride (Buprenorphine SR) in macaques have been reported in only a single case report. In the current study, we evaluated the incidence rate and predictors of b…

Here we describe a case of pseudopregnancy in a New Zealand White rabbit as a result of pair housing with an aggressive conspecific. Clinical signs included fur pulling and nest building that developed shortly after separation from the aggr…

We undertook the present study to investigate the echographic characteristics of the uterus and cervix of female bonnet monkeys ( Macaca radiata ) during the proliferative and secretory phases of the menstrual cycle. The cervix was tortuous…

This study was designed to evaluate the maximal amount of blood that can be safely collected in healthy, adult male and female cynomolgus macaques for 4 consecutive weeks with minimal effect on animal wellbeing. General guidelines for blood…