The values for CA125, TPA, IAP, CEA, and ferritin in sera were measured simultaneously in 68 healthy nonpregnant females and 133 patients with various gynecological diseases, and examined by stepwise discriminant analysis. The usefulness an…
To differentiate pre-operatively between leiomyomata uteri and adenomyosis, we measured serum levels of an antigen (CA 125) common to most nonmucinous epithelial ovarian carcinoma in patients with benign uterine tumor (11 of leiomyomata ute…
In order to investigate the effect of Danazol (D) on serum prolactin (PRL) and cortisol levels, D was given orally in a daily dose of 400 mg for 2 weeks to 4 women (400 mg group) and 600 mg to 5 women (600 mg group) at one month and more af…
Twenty cases (13 from Jichi Medical School Hospital and 7 from other hospitals) of uterine adenomatoid tumor (ADT) were examined histochemically, immunohistochemically and ultrastructurally, to determine the histogenesis. For the control st…
Although we encounter endometriosis not infrequently, the exact nature of this entity has not yet been determined. In order to study the morphogenesis of this disease, we chose the adenomyotic glandular epithelium as distinct ectopic glands…
Clinicopathologic investigations were carried out on 51 cases that had received hysterectomy and had been diagnosed histologically as adenomyosis uteri during a 4-year period since 1977, and the following results were obtained: 1) adenomyos…
It has been established that the pathogenesis of a complete form of testicular feminization syndrome (TFM) is due to end-organ unresponsiveness to androgens. In the present study, two sibling cases with TFM have been reported with special r…
The patients with endometriosis have shown a significant increase in frequency in our country. In the recent years, the incidence of endometriosis in gynecological outpatients is probably 3%. In infertile patients, endometriosis has been de…
This report describes the characteristic features of the exfoliated cells according to histological types, such as the type of early cervical adenocarcinoma for the diagnosis of cervical carcinoma of adenoid type (hereinafter called cervica…
Ascitic fluid was obtained from the patient of ovarian endometrioid cancer. Collected cells were incubated with Eagle's MEM containing 15% fetal calf serum at 37 degrees C under humidified 5% CO2 and 95% air. The epithelial colonies grew ra…
As a treatment for malignant ovarian tumor, whole abdominal irradiation including the upper abdomen is more useful. Between December, 1975 and November, 1980, we additionally applied whole abdominal irradiation by the moving strip technique…
Immunosuppressive acidic protein(IAP) levels were measured in human sera by a single radial immunodiffusion using an IAP plate. Sera were obtained from healthy controls (79 females), patients with myoma uteri (53 cases), patients with benig…
alpha 1-acid glycoprotein (alpha 1AG) in the blood of gynecologic malignancy was measured by the S.R.I.D. method and analyzed by isoelectrofocusing. The usefulness of these methods for diagnosis and prognosis was examined. A. Quantitative a…
The present studies were carried out to clarify the indigenous bacterial flora in the female internal genitalia and surrounding tissues and the pathogenesis of parametritis. Twenty nine patients with uterine tumors which consisted of sixtee…
The effects of human interferon on the growth of xenografted human tumors were studied. Human lymphoblastoid interferon (IFN) was administered intraperitoneally to nude mice with yolk sac tumors of the ovary (YST-1 and YST-2) and endometria…
Relationship between endometrial findings and serum hormone concentrations in patients with functional uterine bleeding (FUB) was not clarified yet. One hundred patients affected by FUB were divided into four groups according to their endom…
A new classification system of endometriosis proposed by the American Fertility Society (AFS classification) was utilized to categorize patients with endometriosis after surgical treatment and the following results were obtained. 1. AFS cla…
The perusal of literatures revealed that simultaneous malignant transformation of predisposing ovarian endometrioid tumor and uterine adenomyosis is a rare occurrence. A case report of endometrioid carcinoma in the right ovary and malignant…
Cases of gynecological tumor mainly uterine benign and malignant tumors were evaluated using 201Thallium-Chloride (201Tl-Cl) after intravenous injection. The positive scans of 100% in 42 cases of uterine myoma including 29 cases of leiomyom…