ObjectivesTo evaluate how UK guidelines for individual health conditions consider coexisting multiple long term conditions and to propose improvements to guideline development processes so that guidelines appropriately account for and consi…
ObjectiveTo estimate the rate of breast cancer associated with use of vaginal oestradiol tablets according to duration and intensity of their use.DesignRegistry based, case-control study, nested in a nationwide cohort.SettingBased in Denmar…
ObjectivesTo evaluate the association between preconception contraceptive use and miscarriage.DesignProspective cohort study.SettingResidents of the United States of America or Canada, recruited from 2013 until the end of 2022.Participants1…
ObjectivesTo identify whether covid-19 vaccines are associated with menstrual changes in order to address concerns about menstrual cycle disruptions after covid-19 vaccination.DesignGlobal, retrospective cohort study of prospectively collec…
The treatment for endometrial cancer is rapidly evolving with the development of molecular analysis and novel strategies. Surgical resection, cytotoxic chemotherapy, endocrine or hormonal treatment, and radiation have been the staples of tr…
ObjectiveTo develop international consensus on the definition and measurement of multimorbidity in research.DesignDelphi consensus study.SettingInternational consensus; data collected in three online rounds from participants between 30 Nove…