Zhonghua yi xue za zhi

OBJECTIVE: To investigate the prevalence of infertility and its risk factors in the fertile-age couples of Beijing, China. METHODS: A cross-sectional survey on the prevalence and risk factors was conducted from July 2007 to May 2008 in 7 B…

OBJECTIVE: To establish the model of cultivating and identifying fibroblast from human endometriosis (HEFC) in vitro. METHODS: The tissues of human endometriotic cysts of ovary were digested by collagenases I, II and IV The resulting cells…

OBJECTIVE: To explore the hospital expenses and hospital stay of surgical management for endometriosis and adenomyosis. METHODS: The average hospital expenses and average hospital stay were compared for a total of 12003 patients of endomet…

OBJECTIVE: To evaluate the effects of PRL-3 siRNA (small interfering RNA) on the migration of endometriotic stromal cells. METHODS: Primary endometriotic stromal cells were cultured in vitro. Then PRL-3 (phosphatase of regenerating liver-3…

OBJECTIVE: To study the expression of nociceptin in adenomyosis tissue and understand its relationship with the severity of dysmenorrhea. METHODS: The myometrial specimens were collected from 55 patients undergoing hysterectomy at our hosp…

OBJECTIVE: To evaluate and compare the efficiency and safety of levonorgestrel-releasing intrauterine system (LNG-IUS) and combined oral contraceptives (COC) in the treatment of recurrent ovarian endometriosis after conservative surgery or …

OBJECTIVE: To investigate the effect and safety of sequential therapy of levofloxacin in the prevention of peri-operative infections among patients undergoing laparoscopic hysterectomy (LH), laparoscopic assisted vaginal hysterectomy (LAVH)…

OBJECTIVE: To study the prognosis of fibroid after ultrasound-guidance percutaneous microwave ablation (PMAUF). METHODS: From Mar. 2007 to Jul.2010 forty uterine fibroids in forty patients with symptoms which were diagnosed in our hospital…

OBJECTIVE: To assess the feasibility of percutaneous microwave ablation in the treatment of diffuse adenomyosis. METHODS: With a mean age of 39.2 years old, 16 patients with symptomatic adenomyosis underwent percutaneous microwave ablation…

OBJECTIVE: To examine and analyze the expression of estrogen receptor-α (ERα) in myometrium of endometrial-myometria interface (EMI) of adenomyosis and normal myometrium and explore the pathogenesis of adenomyosis (ADS). METHODS: The myome…

OBJECTIVE: To construct a latent human soluble tumor necrosis factor receptor I (hsTNFRI) using the latency associated protein (LAP) of transforming growth factor-beta1 (TGF-beta1) fused via a matrix metalloproteinase (MMP) cleavage site to…

OBJECTIVE: To evaluate the complications of different approaches of hysterectomy based on analyzing the records of patients with long post-operative hospitalization. METHODS: The records of 3722 patients undergoing hysterectomy due to beni…

OBJECTIVE: To investigate the long-term effects of androgen combined with low dose all-trans-retinoic acid on myelodysplastic syndrome (MDS). METHODS: Sixty-two MDS patients, 48 with RA, 2 of RAS, 9 with RA with excess of blasts (RAEB), 2 …

OBJECTIVE: To evaluate the association between the susceptibility of endometriosis (EMS) and the gene polymorphism of tumor necrosis factor (TNF) in Chinese Han population. METHODS: Peripheral blood samples were collected from 76 EMS patie…

OBJECTIVE: To investigate the reason why the incidence of endometriosis (EM) is lower in the Uygur women than in the Han women. METHODS: Eutopic and ectopic endometrium samples were obtained by operation and biopsy from 26 EM patients, 10 …

OBJECTIVE: To investigate the diagnosis and treatment of perineal endometriosis. METHODS: The clinical date of 30 patients with perineal endometriosis, aged 32.3 (23 approximately 44), who were admitted 1983 - 2006, operated on, and follow…

OBJECTIVE: To investigate the possible roles of cyclin B1 and cyclin-dependent kanase1 cyclin-dependent kanase1 play in the pathogenesis and development of endometriosis and their association with the ovarian hormones. METHODS: Twenty-nine…

OBJECTIVE: To study the techniques to repair the fascia layer of abdominal wall after the resection of abdominal wall endometriosis (AWE). METHODS: Fifty-five AWE patients aged 28 approximately 38 underwent resection of the lesion. After t…

OBJECTIVE: To study the localization and expression of the vascular endothelial growth factor receptors (VEGFR) Fms-like tyrosine kinase (Flt-1) and kinase insert domain-containing receptor (KDR) in human ectopic and eutopic endometrium of …

OBJECTIVE: To evaluate the clinical effects of the four surgical patterns of hysterectomy for uterine without prolapsis. METHODS: Six hundred and eight patients with different gynecological diseases were operated upon by transvaginal hyste…

OBJECTIVE: To investigate the serum levels of ICAM-1 and its relationship to the extent of the disease. METHODS: Serum sICAM-1 levels of 21 women with endometriosis were measured with a specific enzyme-linked immunosorbent assay, and 21 wo…

OBJECTIVES: To explore the effect of total hysterectomy on sexual behavior in women and to improve the quality of life in posthysterectomic women. METHODS: We observed 107 of patients who had received surgery for more than six months. They…

OBJECTIVE: To evaluate the effects of follicular fluid (FF) from women with endometriosis and tubal factor on sperm binding to zona pellucida under hemizona assay(HZA). METHODS: Follicular fluid was collected at IVF from patients with endo…

203 patients with pelvic endometriosis, all Beijing resident, were collected from the Peking Union Medical College Hospital and the Beijing Obstetrical and Gynecological Hospital. The diagnosis of endometriosis was confirmed by pathological…