Translational psychiatry

· 5 papers in corpus
nonrandomized-trial 2026
doi:10.1038/s41398-026-04334-6 ·PMID:42811022

Depressive and anxiety symptoms prevalent in major depressive disorder (MDD), that affects millions globally, with many patients showing incomplete response to standard treatments. This open-label pilot study evaluated the effects of a 12-w…

other 2025
doi:10.1038/s41398-025-03249-y ·PMID:39939611

Suicide is a complex behavior strongly associated with depression. Despite extensive research, an objective biomarker for evaluating suicide risk precisely and timely is still lacking. Using the precision resting-state fMRI method, we studi…

other 2024
doi:10.1038/s41398-024-03216-z ·PMID:39730323

The high comorbidity of major depressive disorder (MDD) with other diseases has been well-documented. However, the pairwise causal connections for MDD comorbid networks are poorly characterized. We performed Phenome-wide Mendelian randomiza…

other 2023
doi:10.1038/s41398-023-02480-9 ·PMID:37253788

Fluctuations in ovarian steroids across the estrous and menstrual cycle in female rats and women, respectively, are associated with changes in anxiety. Pregnancy causes long-term changes to ovarian hormone release, yet research on estrous- …

review 2016
doi:10.1038/tp.2016.168 ·PMID:27622932

In the central nervous system, bidirectional signaling between glial cells and neurons ('neuroimmune communication') facilitates the development of persistent pain. Spinal glia can contribute to heightened pain states by a prolonged release…