Cancer management and research

Cancer Manag Res · ISSN (print) 1179-1322 · 41 papers in corpus
lab-animal 2020
doi:10.2147/cmar.s252916 ·PMID:33116862

BACKGROUND: Dysregulated circular RNAs (circRNAs) are involved in the development of glioma. This paper aims to analyze the role and mechanism of circRNA tau tubulin kinase 2 (circ-TTBK2) in glioma progression. METHODS: The glioma samples …

review 2020
doi:10.2147/cmar.s233567 ·PMID:32021425

Medicinal plants are a vital source of natural products (NPs) that can cure cancer through modulation of different pathways, including oxidative stress, extrinsic and intrinsic apoptosis, cell cycle, inflammation, NF-kB, PI3K/AKT/mTOR, AMPK…

other 2019
doi:10.2147/cmar.s217362 ·PMID:31576164
review 2019
doi:10.2147/cmar.s204069 ·PMID:31190993

Breast cancer remains the most common cancer among women worldwide. Many patients, especially in our region, are affected while young and during their child-bearing years. Chemotherapy, more commonly used in this age group, may result in pr…

observational 2019
doi:10.2147/CMAR.S187849 ·PMID:30697075

OBJECTIVES: The aim of this study was to evaluate the factors associated with progress-free survival (PFS) and overall survival (OS) in patients with high-grade endometrial stromal sarcoma (HG-ESS). PATIENTS AND METHODS: A total of 40 pati…

observational 2019
doi:10.2147/cmar.s210277 ·PMID:31440090

PURPOSE: Although laparoscopic radical hysterectomy (LRH) has been performed for patients with cervical cancer because of its minimal invasiveness, a recent large prospective study showed that LRH was associated with a lower rate of disease…

lab-animal 2019
doi:10.2147/cmar.s222681 ·PMID:31908532

BACKGROUND: Glioma is a common malignant tumor of the human central nervous system, and the pathological characteristics include invasive growth, angiogenesis, and so on. Ectopic expression of miR-503 works as a critical factor in cancer ce…

review 2019
doi:10.2147/cmar.s231971 ·PMID:31849522

microRNAs (miRNAs) are a class of endogenous short, non-coding RNAs that regulate a multitude of genes at the post-transcriptional level. miR-199, which is a highly conserved miRNA family, consists of miR-199a and miR-199b. Researchers main…

diagnostic-accuracy 2019
doi:10.2147/cmar.s185375 ·PMID:30774440

PURPOSE: To evaluate haptoglobin (Hp) in ovarian cyst fluid as a diagnostic biomarker for epithelial ovarian cancers (EOCs) using surface-enhanced Raman spectroscopy (SERS)-based in vitro diagnostic assay for use in an intraoperative settin…

diagnostic-accuracy 2019
doi:10.2147/cmar.s225672 ·PMID:31849527

OBJECTIVE: To evaluate the accuracy, sensitivity, and specificity of DNA quantitative cytology test for the diagnosis of endometrial cancer or precancerous lesions and then discuss the value of DNA quantitative cytology as a screening tool …

observational 2018
doi:10.2147/cmar.s144850 ·PMID:29563834

IntroductionAdenosquamous carcinoma (ASC) of the bile duct is a rare diagnosis with poorly understood clinicopathological characteristics and disease progression, so identification of the features associated with ASC patient survival is war…

other 2018
doi:10.2147/cmar.s168594 ·PMID:30122983

BACKGROUND: The purpose of this study was to investigate the expression of different miRNAs in nonmetastatic and metastatic endometrial cancer Existing evidence indicates that there are many factors affecting the metastasis of endometrial c…

diagnostic-accuracy 2018
doi:10.2147/cmar.s155693 ·PMID:29861641

PURPOSE: To investigate the diagnostic values of human epididymis protein 4 (HE4), carbohydrate antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), and carcinoembryonic antigen (CEA) for ovarian tumors. METHODS: The participants were …

other 2018
doi:10.2147/cmar.s187156 ·PMID:30519094

BACKGROUND: Ovarian cancer is the major cause of death from cancer among females worldwide. Ovarian clear cell carcinoma (OCCC) is considered a distinct histopathologic subtype with worse prognosis and resistance to conventional chemotherap…

review 2018
doi:10.2147/cmar.s179189 ·PMID:30584363

Ovarian cancer is the most fatal gynecological cancer in the USA and the fifth most common cancer-related cause of death in women. Inflammation has been shown to play many roles in ovarian cancer tumor growth, with the proinflammatory cytok…

meta-analysis 2018
doi:10.2147/cmar.s161876 ·PMID:29713198

PurposeTo comprehensively assess the impact of preoperative serum albumin levels on survival of patients with epithelial ovarian cancer (EOC).Materials and methodsTwo independent researchers searched the PubMed, Embase, and Web of Science d…