Toxicology research

In this developing era, increased anthropogenic activities result in the contamination of natural resources. Different kinds of pollutants threaten the water quality being crucial for the existence of life. There are different sources and r…

Nanomaterials involve an active research and a booming area including different fields (health, environment, electronics, manufacturing, drug delivery). Recently, new concerns are emerging about the risk from increased production and subseq…

An implantation study of cerium oxide nanoparticles (CeO2-NP) combined with 28-day systemic toxicity and genotoxicity studies aligned to current regulatory standards was conducted. The results suggested that local tissue reactions caused by…

Neuronal death caused by inflammatory cytokine-mediated neuroinflammation is being extensively explored. Thioredoxin reductase (TrxR) 2 is a novel mediator of inflammation response. In the current study, we focus on the mechanisms of TrxR2 …

Phytoestrogens are increasingly used as dietary supplements due to their suggested health promoting properties, but also by women for breast enhancement and relief of menopausal symptoms. Generally, phytoestrogens are considered to exert es…

Over the years, various liver-derived in vitro model systems have been developed to enable investigation of the potential adverse effects of chemicals and drugs. Liver tissue slices, isolated microsomes, perfused liver, immortalized cell li…