The aim of this study was to assess the involvement in decidual proliferation of nitric oxide (NO), a regulator of many cellular processes, that is synthesized from L-arginine by NO synthase. The investigation was conducted on pseudopregnan…
The objective of the present study was to examine the zonal changes in endometrial proliferation that occur during the late secretory phase, menses, and postmenstrual endometrial regeneration. We used as our model ovariectomized rhesus monk…
Endometriosis, a disease of women and nonhuman primates in which endometrial tissue grows outside the uterus, can be mimicked surgically in rats and mice. The disease is related to infertility in women, and surgical induction of endometriot…
Previous studies had indicated that the effects of danazol on rat peripheral tissues were mediated through both androgen and estrogen receptors. The purpose of this study was to examine the role of androgen and estrogen receptors in danazol…
Cell-mediated immunity to Chlamydia trachomatis was studied in pregnant women with chlamydial infection of the cervix, in infants born vaginally to these women, and in infants presenting with chlamydial conjunctivitis. Uninfected pregnant w…
The effects of daily subcutaneous injections of 0.2 mg CB-154 (bromocriptine-mesilate), a potent suppressor of pituitary prolactin secretion, between 4 and 11 weeks of age on the occurrence of spontaneous mammary tumors and adenomyosis, a h…
Guanylate cyclase activity was determined in various subcellular fractions of myometrium (1) from rhesus monkeys spayed for at least 6 months and treated either with estradiol-17β (E2) for 14 days or with E2 for 14 days and then for 5 to 14…
The mechanical response of mammalian uterine muscle varies as its hormonal influence changes from estrogen to progesterone dominance. This can be seen in the increase in rate and amplitude of contractions of the uterus and fallopian tubes d…
In the rat prolactin has been shown to exent a luteotropic action an newly formed corpora lutea and a lutmlytic effect on older corpora lutea (1). During each estrous cycle of the rat, luteolysis of corpora lutea from previous cycles occurs…
A prolactin-cocoa butter mixture was implanted once in the median eminence of rats on each of days 1–8 of pregnancy. Control pregnant rats were given similar implants of cocoa butter alone. When laparotomies were performed on day 15, all of…