PNAS nexus

Women make up half the world's population, yet have received relatively little clinical research funding or structural support from major research agencies. Consequently, we know far less about women's health than men's health, including ho…

The Fallopian tube (also called the oviduct) provides the physiological site for fertilization and early embryonic development in mammals, yet its role in shaping preimplantation developmental competence remains incompletely understood. Alt…

Successful embryo implantation requires coordinated changes in the uterine luminal epithelium, including structural adaptations, apical-basal polarity shifts, intrauterine fluid resorption, and cellular communication. Planar cell polarity p…

Locomotion movements are a fundamental characteristic of a variety of species, including prokaryotic and eukaryotic, that has a high impact on essential physiological and pathological processes. For decades, many different authors have focu…

Infertility is associated with the alteration of the seminal microbiome. However, the onset of dysbiosis remains controversial and the involvement of host factors remains elusive. This study investigates the alterations of the seminal micro…

Uterine contraction patterns vary during the ovulatory cycle and throughout pregnancy, but prior measurements have produced limited and conflicting information on these patterns. We combined a virally delivered genetically encoded calcium r…

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a potent AhR ligand, is an environmental contaminant that is known for mediating toxicity across generations. However, whether TCDD can induce multigenerational changes in the expression of microR…