The Journal of neuroscience : the official journal of the Society for Neuroscience

J Neurosci · ISSN (e) 1529-2401 · 2 papers in corpus

other 2013

Vascular endothelial cells mediate mechanical stimulation-induced enhancement of endothelin hyperalgesia via activation of P2X2/3 receptors on nociceptors

doi:10.1523/JNEUROSCI.3229-12.2013 ·PMID:23407944

Endothelin-1 (ET-1) is unique among a broad range of hyperalgesic agents in that it induces hyperalgesia in rats that is markedly enhanced by repeated mechanical stimulation at the site of administration. Antagonists to the ET-1 receptors, …

other 2009

Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation

doi:10.1523/JNEUROSCI.5740-08.2009 ·PMID:19321788

Neurons that produce gonadotropin-releasing hormone (GnRH) are the final common pathway by which the brain regulates reproduction. GnRH neurons are regulated by an afferent network of kisspeptin-producing neurons. Kisspeptin binds to its co…