Archives internationales de pharmacodynamie et de therapie
Arch Int Pharmacodyn Ther
· ISSN (print) 0003-9780
· 3 papers in corpus
The effect of PDE regulators on isolated rat uterus and their probable mechanism of action was investigated. The potassium chloride-induced contracture was enhanced by imidazole (3.67 X 10(-3)M) and potassium bicarbonate (1.5 X 10(-2)M). In…
The metabolism of danazol has been investigated in the rat, the monkey and in human volunteers using 14C-isoxazolo-, 14C-ethynyl, 6,7-tritiated and unlabelled compound. The drug was well absorbed, and rapidly metabolized; approximately 60 e…