ObjectiveThe aim of this study was to compare the therapeutic efficacy of integrating virtual reality technology with conventional pelvic floor rehabilitation therapy versus conventional therapy alone in postpartum women with myofascial pel…
IntroductionAcupuncture has been explored as a potential intervention for POR; however, high-quality evidence is limited. This multicenter randomized trial evaluated the effect of acupuncture on the number of oocytes retrieved following con…
IntroductionDiminished ovarian reserve (DOR) is known to reduce the likelihood of achieving pregnancy or live births in women undergoing in vitro fertilization and embryo transfer (IVF-ET). Acupuncture maybe effective for DOR, but current e…
BackgroundAfter early pregnancy loss (EPL), couples often seek counselling on how long to wait before attempting to conceive again. However, the optimal interpregnancy interval (IPI) between EPL and the next pregnancy is controversial. Addi…
IntroductionEmbryonic stem cells (ESCs), capable of generating all adult cell types, hold transformative potential for agriculture and biomedicine. However, stable sheep ESCs derivation remains challenging, limiting their application in fur…
BackgroundInsulin resistance has been linked to adverse reproductive and pregnancy outcomes. The triglyceride glucose-body mass index (TyG-BMI) serves as a simple and cost-effective surrogate marker of insulin resistance. This study aimed t…
Endometriosis (EMs) is characterized by the establishment and persistence of ectopic lesions, a process fundamentally dependent on aberrant angiogenesis. Endothelial cells (ECs) play a central role in this process; however, accumulating evi…
ObjectiveThis study aims to evaluate and compare the clinical effectiveness of endovascular reintervention vs conservative medical therapy in patients with persistent or recurrent venous-origin chronic pelvic pain (CPP) after initial endova…
Ovarian cancer poses a significant clinical challenge due to its asymptomatic onset and poor prognosis, highlighting the critical need for effective early detection strategies. This study developed a framework that integrates serum proteomi…
Xinrui Wang,1 Yuqing Hou,2 Hongyan Wang2 1School of Nursing, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, People’s Republic of China; 2Gynecology Department, Women’s Hospital School of Medicine Zhejiang University, Hang…
OBJECTIVES: To evaluate the feasibility of quantitative susceptibility mapping (QSM) and R2* mapping in assessing iron deposition in endometriotic ovarian cysts (EMO) and their potential implications for ovarian reserve. MATERIALS AND METH…
IntroductionPCOS is the most common disorder encompassing reproductive, metabolic, and endocrine abnormalities, and has an increased risk of adverse pregnancy and neonatal complications, such as miscarriage, gestational diabetes mellitus, a…
Jingyun Wang,1,* Lu Wang,1,* Xiaohui Wang,1 Ai Ai,1 Ping Qiao2 1Department of Reproductive Medicine, Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Department of …
PURPOSE: Observational studies have indicated a potential link between adenomyosis/endometriosis and adverse pregnancy outcomes (APOs), yet the potential relationship remains uncertain. PATIENTS AND METHODS: This study investigates whether…
ObjectiveThe research focuses on understanding how GSDMD and Caspase-1, key regulators of pyroptosis, influence postoperative recurrence in Endometrial Polyps (EPs) and examines whether a combined biomarker can effectively predict recurrenc…
BackgroundPremature ovarian insufficiency (POI) significantly impairs female fertility and poses substantial health risks; however, its pathogenesis is incompletely understood, and effective therapeutic interventions are limited. Although g…
Background and objectiveIleal ureter replacement (IUR) is the definitive management approach for extensive ureteral strictures (UrSs). Patients with UrS exhibit poor health-related quality of life (HRQoL). We conducted a long-term, multi-in…
PurposeAcute pancreatitis is a common disease with limited supportive treatments. Finding effective biomarkers is of great significance for early diagnosis and therapy, as well as to achieve better prognosis.Materials and methodsThe core ge…
Xiali Wang,1,2,* Shuangping Deng,1,* Xiaoping Pan,3 Guorong Lyu1,21Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, People’s Republic of China; 2Departments of Clinical Medicine, Quanzhou Medi…
ObjectiveTo evaluate the live birth rate (LBR) of assisted reproductive technology (ART) treatment using vitrified donated oocytes in China and to investigate the influencing factors on live birth outcomes.MethodsThis retrospective cohort i…
Endometriosis (EMs) is a chronic gynecological disease with poorly understood pathogenesis. This study integrated lipidomics and transcriptomics to systematically investigate aberrant sphingolipid metabolism in EMs, aiming to identify patho…
BackgroundCervical squamous cell carcinoma (CSCC) exhibits profound spatial heterogeneity in evolutionary trajectories across distinct tumour foci, yet the underlying mechanisms remain poorly understood.MethodsIn this study, we performed an…
Hypoxia stress seriously affects the survival of aquatic animals. However, little is known about the regulation mechanism under hypoxia stress; hence, it is important to fully clarify this regulation to improve the hypoxia tolerance of aqua…
RESEARCH QUESTION: Do iron metabolism and ferroptosis influence oocyte and embryo quality in patients with endometriosis undergoing IVF/intracytoplasmic sperm injection (ICSI), or in a mouse model? DESIGN: Fifty-seven patients with laparos…