Christian Lücht

ORCID: 0000-0001-6527-182X · 1 paper in corpus

2021

Autoantibodies from Patients with Scleroderma Renal Crisis Promote PAR-1 Receptor Activation and IL-6 Production in Endothelial Cells.

International journal of molecular sciences ·doi:10.3390/ijms222111793

BackgroundScleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc). Autoantibodies (Abs) against endothelial cell antigens have been implicated in SSc and SRC. However, their detailed roles remain poorly…