Xinli Hu

ORCID: 0000-0003-4911-5354 · 3 papers in corpus · active 2025-2026

Study types

  • article 2
  • other 1

Condition tags

  • endometriosis 2
  • adenomyosis 2
article 2026
Pathological roles of prolactin signaling in gynecologic and female-predominant diseases and prospects for targeted therapy
·doi:10.1360/csb-2025-5885

Prolactin (PRL) was first identified as a pituitary hormone essential for lactation, but it is now recognized as a pleiotropic regulator of endocrine balance, metabolism, immune function, and tissue remodeling. PRL is secreted systemically …

article 2025
Safety and efficacy of subcutaneous injection with HMI-115 versus placebo in endometriosis-associated pain in premenopausal women: a multicentre, double-blind, randomised, proof-of-concept phase 2 trial
·doi:10.1016/j.lanogw.2025.100032
other 2025
Single-cell RNA sequencing identifies the prolactin receptor as a therapeutic target in adenomyosis
Signal transduction and targeted therapy ·doi:10.1038/s41392-025-02339-z

Adenomyosis is a complex gynecological disease characterized by endometrial tissue invasion into the myometrium. Current interventions, such as hormonal therapy or hysterectomy, are associated with significant side effects and compromise fe…