Marcel Grube

ORCID: 0000-0002-6609-8827 · 8 papers in corpus · active 2020-2024

Study types

  • article 4
  • other 2
  • preprint 2

Condition tags

  • endometriosis 8
  • dysmenorrhea 1
  • infertility 1
  • dyspareunia 1
other 2024
Journal of clinical medicine ·doi:10.3390/jcm13226783

Background: Deep endometriosis (DE) is a special form of endometriosis, one of the most common benign diseases in gynecology. In the specific case of DE, ectopic endometrium can be found not only in peritoneal but also in deeper tissue laye…

other 2024
Journal of clinical medicine ·doi:10.3390/jcm13175039

Background: Endometriosis is known to be a common chronic disease that often affects the quality of life of patients. Especially for deep endometriosis (DE), the most challenging form of the disease, surgery remains an important component o…

article 2022
·doi:10.1055/s-0042-1756999

Objective Multiple forms of endometriosis have been shown to harbour somatic cancer-driver alterations. Previous studies have focused on the inter-patient heterogeneity of genetic alterations in endometriosis, analyzing lesions collected fr…

article 2022
Fertility and sterility ·doi:10.1016/j.fertnstert.2022.05.030

OBJECTIVE: To investigate the heterogeneity of somatic cancer-driver mutations within patients and across endometriosis types. DESIGN: A single-center cohort, retrospective study. SETTING: Tertiary specialist-care center at a university h…

preprint 2021
·doi:10.1101/2021.04.12.21255355

Abstract Endometriosis symptoms are heterogeneous with controversy on whether it constitutes a single disease or multiple distinct types. Our previous work found recurrent somatic cancer-driver alterations in endometriosis; however, these h…

preprint 2021
·doi:10.1101/2021.09.16.21262993

Abstract ARID1A (BAF250a) is a component of the SWI/SNF chromatin modifying complex, plays an important tumor suppressor role, and is considered prognostic in several malignancies. However, in ovarian carcinomas there are contradictory repo…

article 2021
The Journal of Pathology ·doi:10.1002/path.5849

Abstract ARID1A (BAF250a) is a component of the SWI/SNF chromatin modifying complex, plays an important tumour suppressor role, and is considered prognostic in several malignancies. However, in ovarian carcinomas there are contradictory rep…

article 2020
·doi:10.1055/s-0040-1718045

Endometriosis has yielded controversy on whether it constitutes a single disease or distinct types. Current classification systems poorly correlate with the severity of symptoms and do not provide prognostic tools that can guide management …