Elizabeth A. H. Beckett

article 2018

Spinal Glial Adaptations Occur in a Minimally Invasive Mouse Model of Endometriosis: Potential Implications for Lesion Etiology and Persistent Pelvic Pain

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719118773405

Glial adaptations within the central nervous system are well known to modulate central sensitization and pain. Recently, it has been suggested that activity of glial-related proinflammatory cytokines may potentiate peripheral inflammation, …

article 2017

Lesion development is modulated by the natural estrous cycle and mouse strain in a minimally invasive model of endometriosis†

Biology of reproduction ·doi:10.1093/biolre/iox132

Many rodent models of endometriosis are invasive, involving surgery to implant donor endometrial tissue into recipient animals. Moreover, few studies have compared and contrasted lesions between rodent strains and estrous stages without exo…

2016

Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain.

Translational psychiatry ·doi:10.1038/tp.2016.168

In the central nervous system, bidirectional signaling between glial cells and neurons ('neuroimmune communication') facilitates the development of persistent pain. Spinal glia can contribute to heightened pain states by a prolonged release…

article 2014

Characterization of primary afferent spinal innervation of mouse uterus

Frontiers in neuroscience ·doi:10.3389/fnins.2014.00202

The primary afferent innervation of the uterus is incompletely understood. The aim of this study was to identify the location and characteristics of primary afferent neurons that innervate the uterine horn of mice and correlate the differen…