Mathew Leonardi

Social media platforms are used for support and as resources by people from the endometriosis community who are seeking advice about diagnosis, education, and disease management. However, little is known about the scientific accuracy of inf…

Background and Aims: Currently, it takes an average of 6.4 years to obtain a diagnosis for endometriosis. To address this delay, the IMAGENDO project combines ultrasounds (eTVUS) and Magnetic Resonance Images (eMRI) using Artificial Intelli…

Background and Aims: Numerous endometriosis treatments exist, ranging from surgical to traditional medications to complementary and alternative medicines (CAMs). The ranking of treatments across management categories remains unknown. To add…

PURPOSE: The anatomical distribution of deep endometriosis (DE) is essential in treating patients with symptoms associated with the disease. There is an evidence gap in correlating clinical features and symptoms with disease patterns. The s…

This presentation focused on evaluating uterosacral ligaments, crucial anatomical structures supporting the uterus within the pelvic cavity. These ligaments are the most common site of deep endometriosis. Historically, it was thought that n…

There is a growing interest in the endocannabinoid system and the gut microbiota. Both areas have been suggested to play a role in endometriosis, however this is yet to be studied comprehensively. The purpose of this narrative review is to …

Endometriosis, a chronic condition affecting around 10-14% of women, is challenging to manage, due to its complex pathogenesis and limited treatment options. Research has suggested a potential role of the gut microbiota and the endocannabin…

There is a growing interest in the endocannabinoid system and the gut microbiota. Both areas have been suggested to play a role in endometriosis, however this is yet to be studied comprehensively. The purpose of this narrative review is to …

The Canadian Association of Radiologists (CAR) Endometriosis Working Group was tasked with providing guidance and benchmarks to ensure the quality of technique and interpretation for advanced imaging modalities associated with diagnosing en…

Purpose: The Canadian Association of Radiologists (CAR) Endometriosis Working Group developed a national survey to evaluate current practice patterns associated with imaging endometriosis using advanced pelvic ultrasound and MRI to inform f…

This presentation focuses on the utility of ultrasound in diagnosing superficial endometriosis, a challenging condition to detect using traditional imaging methods. Superficial endometriosis refers to lesions on the surface of pelvic organs…

The identification of an obliterated cul-de-sac in patients with a retroverted uterus due to endometriosis is crucial for proper evaluation of the complexity of surgery for patients with advanced disease. However, the traditional sliding si…

The primary objective of this study is to determine the correlation between predicted surgical times using endometriosis ultrasound (US) with actual surgical times. Secondary objectives include determining the: 1) correlation between surgeo…

STUDY OBJECTIVE: Externally validate the American Association of Gynecologic Laparoscopists (AAGL) staging system against surgical complexity and compare diagnostic accuracy with revised American Society for Reproductive Medicine (rASRM) st…

Endometriosis affects 1 in 9 women, taking 6.4 years to diagnose using conventional laparoscopy. Non-invasive imaging enables timelier diagnosis, reducing diagnostic delay, risk and expense of surgery. This review updates literature explori…

The uterosacral ligaments (USLs) and torus uterinus (TU) are common sites for deep endometriosis (DE) but are challenging to diagnose through transvaginal ultrasound (TVS). Anatomical distortion caused by severe endometriosis, including pou…

An up-to-date description of ovarian and deep endometriosis distribution is necessary as the diagnostic algorithm now includes ultrasound as a highly specific diagnostic test. The primary objective was to describe ovarian/deep endometriosis…

The primary objective of this study is to establish whether ultrasound (US) diagnosis of endometriosis affects patient decision-making on treatment options. Secondary objectives include determining: 1) patient comfort of endometriosis US; 2…

Endometriosis is a complex chronic inflammatory process characterised by the presence of endometrial-like glandular tissue outside the uterine cavity, typically within the pelvic structures. This condition affects up to 10-15 % of women and…

Endometriosis is a debilitating condition affecting 5% to 10% of the women worldwide, where early detection and treatment are the best tools to manage the condition. Early detection can be done via surgery, but multi-modal medical imaging i…

INTRODUCTION: It is recognized that for individuals living with endometriosis, receiving a diagnosis is psychosocially beneficial, but little is known about whether this is influenced by the way in which the disease is diagnosed. The primar…

Videoclip S1. A presentation of the triangle sign and a comprehensive guide on its execution and significance. Videoclip S2. A demonstration of a negative triangle sign with surgical confirmation. Please note: The publisher is not responsib…

Uterine fibroids are common benign tumors that occur in up to 80% of women. Approximately half of the women affected experience considerable physical, psychological, and economic burdens and impact on quality of life due to symptoms such as…