Lori A. Brotto

OBJECTIVE: To evaluate the prevalence and characteristics of recreational cannabis use in women with pelvic pain, and to examine the influence of cannabis legalization on these parameters. METHODS: We conducted a retrospective analysis of …

INTRODUCTION: Dyspareunia affects 8%-22% of women worldwide and an unknown number of gender-diverse people. Dyspareunia is commonly categorized into deep and superficial subtypes based on pain location and underlying etiology; however, curr…

BACKGROUND: Colorectal cancer (CRC) affects a growing number of females. Our objective was to evaluate the impact of CRC on sexual health outcomes among females, while controlling for age. METHODS: We conducted a cohort study using adminis…

To correlate pain-related phenotyping for central nervous system sensitization in endometriosis-associated pain with mental health outcomes during the COVID-19 pandemic, the prospective Endometriosis and Pelvic Pain Interdisciplinary Cohort…

BACKGROUND: Deep dyspareunia affects 50% of people with endometriosis. The Ohnut is a set of interlocking rings that fit over the penis/insertive object. One or more rings can be used to limit insertion depth and reduce deep dyspareunia. A…

Abstract Introduction Among individuals with endometriosis, approximately 50% experience deep dyspareunia. There is a validated test to evaluate superficial dyspareunia (tampon test); however, no such test exists for deep dyspareunia. Thus,…

Abstract Introduction Approximately 10% of reproductive-age females are affected by endometriosis, and of those, ~50% suffer from deep dyspareunia (DD). A portion of those with DD do not respond to medical and surgical treatments and theref…

BACKGROUND: Approximately half of people with endometriosis experience deep dyspareunia; however, there is no means of objective self-testing of endometriosis-associated deep dyspareunia. AIM: The aim of this study was to assess the accept…

Endometriosis-associated dyspareunia can persist after surgical interventions, requiring multidisciplinary treatment including pain education. This study explored the effectiveness of a one-day workshop for improving knowledge, behavioural …

OBJECTIVE: Myofascial tenderness is present in most chronic pelvic pain conditions and causes significant distress to patients. Treatment is challenging and often not curative. Cannabis is often used for self-management of chronic pelvic pa…

BACKGROUND: Endometriosis-associated deep dyspareunia is associated with reduced sexual quality of life, lower self-esteem, and impaired sexual function. OBJECTIVE: The primary objective is to assess the acceptability of a phallus length r…

Objective The increased stress the globe has experienced with the COVID-19 pandemic has affected mental health, disproportionately affecting women. However, how perceived stress in the first year affected menstrual and menopausal symptoms h…

BACKGROUND Endometriosis-associated deep dyspareunia is associated with reduced sexual quality of life, lower self-esteem, and impaired sexual function. OBJECTIVE The primary objective is to assess the acceptability of a phallus length r…

ABSTRACT Introduction Deep dyspareunia negatively impacts people living with endometriosis and their sexual relationships. We are conducting a pilot study to assess the acceptability of 1) a silicone buffer (brand: OhNut) worn by the penetr…

OBJECTIVES: The SARS-CoV-2 (COVID-19) pandemic has had profound physical and mental health effects on populations around the world. Limited empirical research has used a gender-based lens to evaluate the mental health impacts of the pandemi…

INTRODUCTION: Pelvic pain and vulvar pain are common conditions in women. In this study, we sought to characterize the clinical picture of patients with concurrent pelvic pain and provoked vestibulodynia (PVD). AIM: To analyze the associat…

INTRODUCTION: Deep dyspareunia is a common symptom in women, including in half of women with endometriosis, but little is known about its response to treatment and predictors of persistent deep dyspareunia over time. AIM: To follow up deep…

INTRODUCTION: Little is known about women with concurrent diagnoses of deep dyspareunia and superficial dyspareunia. AIM: The aim of this study was to determine the prevalence, associations, and outcome of women with concurrent deep-superf…

The etiology of deep dyspareunia in endometriosis is unclear. Our objective was to determine whether nerve bundle density in the cul-de-sac/uterosacrals (zone II) is associated with deep dyspareunia in women with endometriosis. We conducted…

Circulating endothelial progenitor cells are up‐regulated in a mouse model of endometriosis. CM Becker, P Beaudry, T Funakoshi, O Benny, A Zaslavsky, D Zurakowski, J Folkman, RJ D'Amato, S Ryeom. Am J Pathol 2011;178:1782–91.