Harold Snieder

No ORCID on file · 10 papers in corpus · active 1998-2026

Study types

  • other 3
  • article 1

Condition tags

  • endometriosis 3
  • irritable_bowel_syndrome 1
2026
Nature human behaviour ·doi:10.1038/s41562-026-02476-7

Anxiety is heritable and exists on a continuum, with symptoms ranging from adaptive threat response to clinical disorder. Here we performed a genome-wide association meta-analysis of generalized anxiety symptom severity in 693,869 individua…

other 2025
medRxiv : the preprint server for health sciences ·doi:10.1101/2025.07.10.25331321

We performed a genome-wide association meta-analysis of generalised anxiety symptom severity in 696,563 individuals of European ancestry from 14 cohorts. We identified 82 independent genome-wide significant variants within 76 loci, 41 of wh…

other 2023
Nature human behaviour ·doi:10.1038/s41562-023-01528-6

Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertility and identify alleles under present-day selection. Using data in 785,604 individuals of European ancestry, we identified 43 genomic loci a…

2021
Nature human behaviour ·doi:10.1038/s41562-021-01135-3

Age at first sexual intercourse and age at first birth have implications for health and evolutionary fitness. In this genome-wide association study (age at first sexual intercourse, N = 387,338; age at first birth, N = 542,901), we identify…

2020
Nature communications ·doi:10.1038/s41467-020-19742-5

Miscarriage is a common, complex trait affecting ~15% of clinically confirmed pregnancies. Here we present the results of large-scale genetic association analyses with 69,054 cases from five different ancestries for sporadic miscarriage, 75…

other 2019
Frontiers in sociology ·doi:10.3389/fsoc.2019.00074

Biological, genetic, and socio-demographic factors are all important in explaining reproductive behavior, yet these factors are typically studied in isolation. In this study, we explore an innovative sociogenomic approach, which entails inc…

2017
European journal of human genetics : EJHG ·doi:10.1038/ejhg.2017.105

Previous research has found a genetic component of human reproduction and childlessness. Others have argued that the heritability of reproduction is counterintuitive due to a frequent misinterpretation that additive genetic variance in repr…

2016
Nature genetics ·doi:10.1038/ng.3698

The genetic architecture of human reproductive behavior-age at first birth (AFB) and number of children ever born (NEB)-has a strong relationship with fitness, human development, infertility and risk of neuropsychiatric disorders. However, …

2015
PloS one ·doi:10.1371/journal.pone.0126821

Research on genetic influences on human fertility outcomes such as number of children ever born (NEB) or the age at first childbirth (AFB) has been solely based on twin and family-designs that suffer from problematic assumptions and practic…

article 1998
·doi:10.1210/jcem.83.6.4890

A classical twin study was performed to assess the extent to which genetic factors explain individual differences in age at menopause and (indications for) hysterectomy. It was further examined whether a genetic effect on the timing of the …