Clemente V

ORCID: 0000-0003-1086-0971 · 1 paper in corpus · active 2022
2022
GLS1 is a protective factor in patients with ovarian clear cell carcinoma and its expression does not correlate with ARID1A-mutated tumors.
Cancer research communications ·doi:10.1158/2767-9764.crc-22-0122

Targeting glutamine metabolism has emerged as a novel therapeutic strategy for several human cancers, including ovarian cancer. The primary target of this approach is the kidney isoform of glutaminase, glutaminase 1 (GLS1), a key enzyme in …