Brüggemann K

No ORCID on file · 3 papers in corpus · active 2013-2022

Study types

  • article 1
  • other 1

Condition tags

  • endometriosis 2
  • die_deep_infiltrating 1
2022
Knockdown of the stem cell marker Musashi-1 inhibits endometrial cancer growth and sensitizes cells to radiation.
Stem cell research & therapy ·doi:10.1186/s13287-022-02891-3

BackgroundEndometrial carcinoma is the most common gynecological cancer in Europe. Musashi-1 is known to be a key regulator of endometrial cancer stem cells and a negative prognostic marker. In the present study, we aimed to understand grow…

article 2019
γ‐Secretase inhibition affects viability, apoptosis, and the stem cell phenotype of endometriotic cells
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/aogs.13707

INTRODUCTION: Stem cells mediate cyclic regeneration of the endometrium. The upregulated expression of receptors and modulators of the notch signaling pathway in endometriosis suggests an involvement in the pathogenetic process. Here, we in…

other 2013
MicroRNA miR-145 inhibits proliferation, invasiveness, and stem cell phenotype of an in vitro endometriosis model by targeting multiple cytoskeletal elements and pluripotency factors
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.11.055

OBJECTIVE: To study the function of miR-145, known to be dysregulated in endometriosis, and to identify its target genes in an in vitro endometriosis model. DESIGN: Experimental laboratory study. SETTING: University medical centers. PATI…