Siwicki RA

ORCID: 0000-0002-2061-3782 · 1 paper in corpus · active 2023
2023
PIK3CA mutation in endometriotic epithelial cells promotes viperin-dependent inflammatory response to insulin.
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01094-6

Endometrial epithelia are known to harbor cancer driver mutations in the absence of any pathologies, including mutations in PIK3CA. Insulin plays an important role in regulating uterine metabolism during pregnancy, and hyperinsulinemia is a…