Dalton JT

ORCID: 0000-0002-3915-7326 · 2 papers in corpus · active 2005-2007
2007
Selective Androgen Receptor Modulator (SARM) treatment prevents bone loss and reduces body fat in ovariectomized rats.
Pharmaceutical research ·doi:10.1007/s11095-006-9152-9

PurposeThis study was conducted to examine the bone and body composition effects of S-4, an aryl-propionamide derived Selective Androgen Receptor Modulator (SARM) in an ovariectomy induced model of accelerated bone loss.MethodsOne hundred t…

2005
Discovery and therapeutic promise of selective androgen receptor modulators.
Molecular interventions ·doi:10.1124/mi.5.3.7

Androgens are essential for male development and the maintenance of male secondary characteristics, such as bone mass, muscle mass, body composition, and spermatogenesis. The main disadvantages of steroidal androgens are their undesirable p…