Padler-Karavani V

ORCID: 0000-0002-4761-3571 · 1 paper in corpus · active 2011
2011
Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer.
Cancer research ·doi:10.1158/0008-5472.can-10-4102

Human carcinomas can metabolically incorporate and present the dietary non-human sialic acid Neu5Gc, which differs from the human sialic acid N-acetylneuraminic acid (Neu5Ac) by 1 oxygen atom. Tumor-associated Neu5Gc can interact with low l…