Wendy V Ingman

No ORCID on file · 5 papers in corpus · active 2009-2019

Study types

  • article 3
  • other 2

Condition tags

  • endometriosis 4
  • dysmenorrhea 1
other 2019
Macrophages infiltrating endometriosis-like lesions exhibit progressive phenotype changes in a heterologous mouse model
Journal of reproductive immunology ·doi:10.1016/j.jri.2019.01.002

Endometriotic lesion development involves complex interactions between endometrial tissue, the peritoneum and immune cells. Macrophages are essential in this process; however their precise roles are not defined. To investigate whether infil…

other 2012
Host-derived TGFB1 deficiency suppresses lesion development in a mouse model of endometriosis
The American journal of pathology ·doi:10.1016/j.ajpath.2011.11.013

Transforming growth factor-β1 (TGFB1) is a multifunctional cytokine that is abundant in both endometriotic lesions and the peritoneal fluid in women with endometriosis. However, the role of TGFB1 in the development of endometriosis is as ye…

article 2010
133. LESION WEIGHT AND GLANDULAR DEVELOPMENT ARE SUPPRESSED IN A TGFB1 DEFICIENT MOUSE MODEL OF ENDOMETRIOSIS
·doi:10.1071/srb10abs133

Endometriosis causes subfertility, pelvic pain and dysmenorrhea, and affects 10% of women of reproductive age globally. The pathology of endometriosis is still poorly understood; however microarray data from a mouse model revealed transform…

article 2010
An essential role for macrophages in corpus luteum function and early pregnancy maintenance
·doi:10.1016/j.jri.2010.06.115
article 2009
507. TGFβ REGULATES ENDOMETRIOSIS-LIKE LESION DEVELOPMENT IN MICE INDEPENDENTLY OF THE RUNX-2/OPN PATHWAY
·doi:10.1071/srb09abs507

TGFβ is likely to significantly influence endometriotic lesion development, as TGFβ KO/SCID mice with no host-derived TGFβ activity have smaller human ectopic endometrial lesions than control mice. TGFβ potentially acts via RUNX2, a transcr…