Jaclyn R Patterson

No ORCID on file · 1 paper in corpus · active 2010

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2010
Bioorganic & medicinal chemistry letters ·doi:10.1016/j.bmcl.2009.10.092

The previously reported pyrrolidine class of progesterone receptor partial agonists demonstrated excellent potency but suffered from serious liabilities including hERG blockade and high volume of distribution in the rat. The basic pyrrolidi…