Van den Veyver IB

lab-animal 2021

Reproductive Outcomes from Maternal Loss of Nlrp2 Are Not Improved by IVF or Embryo Transfer Consistent with Oocyte-Specific Defect

Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-020-00360-x

Nlrp2 encodes a protein of the oocyte subcortical maternal complex (SCMC), required for embryo development. We previously showed that loss of maternal Nlrp2 in mice causes subfertility, smaller litters with birth defects, and growth abnorma…

other 2015

A genome-wide screen for copy number alterations in an adolescent pilot cohort with müllerian anomalies

Fertility and sterility ·doi:10.1016/j.fertnstert.2014.10.044

OBJECTIVE: To examine whether pathogenic copy number changes (CNCs) can be identified in deoxyribonucleic acid from females with different classes of müllerian anomalies. DESIGN: We conducted array-based copy number variant (CNV) analysis …

observational 2015

No evidence for mutations in NLRP7, NLRP2 or KHDC3L in women with unexplained recurrent pregnancy loss or infertility

Human reproduction (Oxford, England) ·doi:10.1093/humrep/deu296

STUDY QUESTION: Are mutations in NLRP2/7 (NACHT, LRR and PYD domains-containing protein 2/7) or KHDC3L (KH Domain Containing 3 Like) associated with recurrent pregnancy loss (RPL) or infertility? SUMMARY ANSWER: We found no evidence for mu…