James B. Bussel

Abstract Immune thrombocytopenia purpura(ITP) is one of the most common causes of acquired thrombocytopenia. Although ITP is believed to result from autoreactive antibodies that lead to platelet destruction, its exact pathogenesis is not kn…

Abstract Background: GMA161 is a humanized version of a monoclonal anti-Fcγ-RIII antibody, 3G8, that was in clinical trial in the second half of the 1980s. Infusion of 25 mg of 3G8 (0.25–0.5mg/kg) resulted in transient but dramatic response…