Salama A. Salama

ORCID: 0000-0001-6129-6616 · 4 papers in corpus
lab-animal 2021
Glucose and fatty acid metabolism involved in the protective effect of metformin against ulipristal-induced endometrial changes in rats
Scientific reports ·doi:10.1038/s41598-021-88346-w

Ulipristal acetate (UPA) is effective in the treatment of uterine fibroids. However, its clinical use is hampered by the development of pathologic progesterone receptor modulator-associated endometrial changes (PAECs). The current study was…

other 2017
Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases
BioMed research international ·doi:10.1155/2017/5316845

The role of the extracellular matrix (ECM) in uterine fibroids (UF) has recently been appreciated. Overhydroxylation of lysine residues and the subsequent formation of hydroxylysylpyridinoline (HP) and lysylpyridinoline (LP) cross-links und…

lab-animal 2009
Effect of tumor necrosis factor-alpha on estrogen metabolism and endometrial cells: potential physiological and pathological relevance
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2008-1389

CONTEXT: Estrogen and its metabolites play a critical role in the pathophysiology of the endometrium. The bioavailability of estrogen and estrogen metabolites in endometrial tissues depends on the expression of enzymes involved in estrogen …

lab-animal 2008
Expression and cyclic variations of catechol-O-methyl transferase in human endometrial stroma
Fertility and sterility ·doi:10.1016/j.fertnstert.2007.01.042

OBJECTIVE: To investigate the role of catechol-O-methyl transferase (COMT) in the regulation of estrogen metabolism in human endometrium. DESIGN: Laboratory study. SETTING: Academic research laboratory. INTERVENTION(S): Immunohistochemis…